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DNMT3L 抗体 (AA 43-421)

This 兔 多克隆 anti-DNMT3L antibody specifically detects DNMT3L in WB, ELISA 和 FACS. The antibody is reactive with 小鼠 和 大鼠 samples.
产品编号 ABIN7601723
发货至: 中国
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北京 101111
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Quick Overview for DNMT3L 抗体 (AA 43-421) (ABIN7601723)

抗原

See all DNMT3L (TRDMT1) 抗体
DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

适用

  • 72
  • 17
  • 3
小鼠, 大鼠

宿主

  • 66
  • 11

克隆类型

  • 68
  • 9
多克隆

标记

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This DNMT3L antibody is un-conjugated

应用范围

  • 61
  • 36
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  • 6
  • 6
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  • 3
  • 3
  • 2
  • 2
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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 8
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    • 5
    • 5
    • 4
    • 2
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    • 1
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    AA 43-421

    原理

    Anti-Dnmt3l Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Dnmt3l Antibody (ABIN7601723). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Dnmt3l recombinant protein (Position: A43-L421).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
    ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

    别名

    Dnmt3l

    背景

    Synonyms: Transforming acidic coiled-coil-containing protein 1,Gastric cancer antigen Ga55,Taxin-1,TACC1,KIAA1103,

    Tissue Specificity: Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues. Down-regulated in a subset of cases of breast cancer. .

    Background: DNA (cytosine-5)-methyltransferase 3-like is an enzyme that in humans is encoded by the DNMT3L gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein that is a catalytically inactive regulatory factor of DNA methyltransferases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    分子量

    44 kDa

    基因ID

    54427
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