DNMT3L 抗体 (AA 43-421)
Quick Overview for DNMT3L 抗体 (AA 43-421) (ABIN7601723)
抗原
See all DNMT3L (TRDMT1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 43-421
-
原理
- Anti-Dnmt3l Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Dnmt3l Antibody Picoband® (ABIN7601723). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived mouse Dnmt3l recombinant protein (Position: A43-L421).
-
亚型
- IgG
-
-
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 1-386) antibody
TRDMT1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 147-386) antibodyTRDMT1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2D10H11 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) antibodyTRDMT1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (Internal Region) antibodyTRDMT1 适用: 人, 小鼠 WB, ELISA, IHC, IF, IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 1-386) antibodyTRDMT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 1-234) antibodyTRDMT1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 1-386) antibodyTRDMT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 357-388), (C-Term) antibodyTRDMT1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB02219 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 150-175) antibodyTRDMT1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) (AA 383-417), (C-Term) antibodyTRDMT1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB50995 unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Aapola, U., Shibuya, K., Scott, H. S., Ollila, J., Vihinen, M., Heino, M., Shintani, A., Kawasaki, K., Minoshima, S., Krohn, K., Antonarakis, S. E., Shimizu, N., Kudoh, J., Peterson, P. Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cysteine-5-methyltransferase 3 gene family. Genomics 65: 293-298, 2000. 2. Bourc'his, D., Bestor, T. H. Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L. Nature 431: 96-98, 2004. 3. Bourc'his, D., Xu, G.-L., Lin, C.-S., Bollman, B., Bestor, T. H. Dnmt3L and the establishment of maternal genomic imprints. Science 294: 2536-2539, 2001. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
-
别名
- Dnmt3l
-
背景
-
Synonyms: Transforming acidic coiled-coil-containing protein 1,Gastric cancer antigen Ga55,Taxin-1,TACC1,KIAA1103,
Tissue Specificity: Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues. Down-regulated in a subset of cases of breast cancer. .
Background: DNA (cytosine-5)-methyltransferase 3-like is an enzyme that in humans is encoded by the DNMT3L gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein that is a catalytically inactive regulatory factor of DNA methyltransferases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
-
分子量
- 44 kDa
-
基因ID
- 54427
抗原
-
