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ATF6 抗体 (AA 423-670)

This anti-ATF6 antibody is a 兔 多克隆 antibody detecting ATF6 in WB, ELISA, IF, ICC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601704
发货至: 中国

Quick Overview for ATF6 抗体 (AA 423-670) (ABIN7601704)

抗原

See all ATF6 抗体
ATF6 (Activating Transcription Factor 6 (ATF6))

适用

  • 94
  • 43
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  • 6
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  • 4
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  • 3
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 88
  • 10
  • 1

克隆类型

  • 88
  • 11
多克隆

标记

  • 54
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ATF6 antibody is un-conjugated

应用范围

  • 84
  • 31
  • 27
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  • 24
  • 21
  • 17
  • 15
  • 9
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  • 7
  • 3
  • 3
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  • 1
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

    • 16
    • 15
    • 13
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 423-670

    原理

    Anti-ATF6 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-ATF6 Antibody Picoband® (ABIN7601704). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ATF6 recombinant protein (Position: A423-Q670).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Li, M., Baumeister, P., Roy, B., Phan, T., Foti, D., Luo, S., Lee, A. S. : ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1. Molec. Cell. Biol. 20: 5096-5106, 2000. 2. Thameem, F., Farook, V. S., Bogardus, C., Prochazka, M. : Association of amino acid variants in the activating transcription factor 6 gene (ATF6) on 1q21-q23 with type 2 diabetes in Pima Indians. Diabetes 55: 839-842, 2006.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    ATF6 (Activating Transcription Factor 6 (ATF6))

    别名

    ATF6

    背景

    Synonyms: Cyclic AMP-dependent transcription factor ATF-6 alpha,cAMP-dependent transcription factor ATF-6 alpha,Activating transcription factor 6 alpha,ATF6-alpha,Processed cyclic AMP-dependent transcription factor ATF-6 alpha,ATF6,

    Tissue Specificity: Ubiquitous.

    Background: ATF6, a member of the leucine zipper protein family, is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules. This gene is mapped to chromosome 1q23.3. ATF6 can constitutively induce the promoter of glucose-regulated protein (grp) genes through activation of the endoplasmic reticulum (ER) stress element (ERSE).

    分子量

    90-100 kDa

    基因ID

    22926

    UniProt

    P18850

    途径

    ER-Nucleus Signaling, Unfolded Protein Response
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