MMP2 抗体 (AA 412-573)
Quick Overview for MMP2 抗体 (AA 412-573) (ABIN7601678)
抗原
See all MMP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 412-573
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原理
- Anti-MMP2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MMP2 Antibody Picoband® (ABIN7601678). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MMP2 recombinant protein (Position: E412-N573).
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亚型
- IgG
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anti-Matrix Metalloproteinase 2 (MMP2) (AA 31-109) antibody
MMP2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 40-280) antibodyMMP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) antibodyMMP2 适用: 人 WB, IP, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 401-500) antibodyMMP2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 110-660) antibodyMMP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 9-140) antibodyMMP2 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2B11E6 unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (C-Term) antibodyMMP2 适用: 人, 大鼠, 小鼠, 兔, Cow, 犬, 马, 豚鼠, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 110-660) antibodyMMP2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 242-396) antibodyMMP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1E2 unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 9-140) antibodyMMP2 适用: 人, 小鼠 宿主: 小鼠 Monoclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Nagase, H., Barrett, A. J., Woessner, J. F., Jr. : Nomenclature and glossary of the matrix metalloproteinases. Matrix Suppl. 1: 421-424, 1992. 2. Collier, I. E., Bruns, G. A. P., Goldberg, G. I., Gerhard, D. S. : On the structure and chromosome location of the 72- and 92- kDa human type IV collagenase genes. Genomics 9: 429-434, 1991. 3. Huhtala, P., Chow, L. T., Tryggvason, K. : Structure of the human type IV collagenase gene. J. Biol. Chem. 265: 11077-11082, 1990. 4. Irwin, J. C., Kirk, D., Gwatkin, R. B. L., Navre, M., Cannon, P., Giudice, L. C. : Human endometrial matrix metalloproteinase-2, a putative menstrual proteinase: hormonal regulation in cultured stromal cells and messenger RNA expression during the menstrual cycle. J. Clin. Invest. 97: 438-447, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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别名
- MMP2
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背景
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Synonyms: 72 kDa type IV collagenase,3.4.24.24,72 kDa gelatinase,Gelatinase A,Matrix metalloproteinase-2,MMP-2,TBE-1,PEX,MMP2,CLG4A,
Tissue Specificity: Produced by normal skin fibroblasts. PEX is expressed in a number of tumors including gliomas, breast and prostate. .
Background: Matrix metalloproteinase-2 (MMP2) is a Type IV collagenase, 72-kD, which is also known as gelatinase and is a member of a group of secreted zinc metalloproteases. The MMP2 gene is 17 kb long with 13 exons varying in size from 110 to 901 bp and 12 introns ranging from 175 to 4,350 bp, located within a region of human chromosome 16q13. In addition, the extra exons encode the amino acids of the fibronectin-like domain which has so far been found in only the 72- and 92- kDa type IV collagenase. MMP2, which has a critical role in the binding of progelatinase A and TIMP4 via the C-terminal hemopexin-like domain (C domain), is functionally associated on the surface of angiogenic blood vessels. Not only is a likely effector of endometrial menstrual breakdown, MMP2 is also effector and regulator of the inflammatory response. Moreover, MMP2 could be helpful in diagnosing Takayasu arteritis.
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分子量
- 70 kDa
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基因ID
- 4313
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UniProt
- P08253
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途径
- Activation of Innate immune Response
抗原
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