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ADAM8 抗体 (AA 41-290)

This anti-ADAM8 antibody is a 兔 多克隆 antibody detecting ADAM8 in WB, ELISA 和 FACS. Suitable for 人 和 大鼠.
产品编号 ABIN7601664
发货至: 中国

Quick Overview for ADAM8 抗体 (AA 41-290) (ABIN7601664)

抗原

See all ADAM8 抗体
ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

适用

  • 57
  • 24
  • 6
  • 3
  • 3
  • 1
人, 大鼠

宿主

  • 50
  • 8
  • 3

克隆类型

  • 52
  • 9
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ADAM8 antibody is un-conjugated

应用范围

  • 37
  • 24
  • 20
  • 16
  • 14
  • 8
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 16
    • 10
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 41-290

    原理

    Anti-MS2/ADAM8 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-MS2/ADAM8 Antibody Picoband® (ABIN7601664). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MS2/ADAM8 recombinant protein (Position: R41-L290).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Hernandez, I., Moreno, J. L., Zandueta, C., Montuenga, L., Lecanda, F. Novel alternatively spliced ADAM8 isoforms contribute to the aggressive bone metastatic phenotype of lung cancer. Oncogene 29: 3758-3769, 2010. 2. Higuchi, Y., Kataoka, M., Yamamoto, S. MS2 (ADAM 8), a myelomonocytic cell surface antigen: expression, chromosomal localization and production of truncated ADAM 8 transgenic mice. (Abstract) Tissue Antigens 48: 423 only, 1996. 3. Kelly, K., Hutchinson, G., Nebenius-Oosthuizen, D., Smith, A. J. H., Bartsch, J. W., Horiuchi, K., Rittger, A., Manova, K., Docherty, A. J. P., Blobel, C. P. Metalloprotease-disintegrin ADAM8: expression analysis and targeted deletion in mice. Dev. Dyn. 232: 221-231, 2005.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

    别名

    ADAM8

    背景

    Synonyms: Calretinin, CR, 29 kDa calbindin, CALB2, CAB29

    Tissue Specificity: Brain.

    Background: A Disintegrin and metalloproteinase domain-containing protein 8 is an enzyme that in humans is encoded by the ADAM8 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.

    分子量

    80 kDa

    基因ID

    101

    UniProt

    P78325

    途径

    Activation of Innate immune Response, M Phase
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