ADAM8 抗体 (AA 41-290)
Quick Overview for ADAM8 抗体 (AA 41-290) (ABIN7601664)
抗原
See all ADAM8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 41-290
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原理
- Anti-MS2/ADAM8 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-MS2/ADAM8 Antibody Picoband® (ABIN7601664). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MS2/ADAM8 recombinant protein (Position: R41-L290).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hernandez, I., Moreno, J. L., Zandueta, C., Montuenga, L., Lecanda, F. Novel alternatively spliced ADAM8 isoforms contribute to the aggressive bone metastatic phenotype of lung cancer. Oncogene 29: 3758-3769, 2010. 2. Higuchi, Y., Kataoka, M., Yamamoto, S. MS2 (ADAM 8), a myelomonocytic cell surface antigen: expression, chromosomal localization and production of truncated ADAM 8 transgenic mice. (Abstract) Tissue Antigens 48: 423 only, 1996. 3. Kelly, K., Hutchinson, G., Nebenius-Oosthuizen, D., Smith, A. J. H., Bartsch, J. W., Horiuchi, K., Rittger, A., Manova, K., Docherty, A. J. P., Blobel, C. P. Metalloprotease-disintegrin ADAM8: expression analysis and targeted deletion in mice. Dev. Dyn. 232: 221-231, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))
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别名
- ADAM8
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背景
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Synonyms: Calretinin, CR, 29 kDa calbindin, CALB2, CAB29
Tissue Specificity: Brain.
Background: A Disintegrin and metalloproteinase domain-containing protein 8 is an enzyme that in humans is encoded by the ADAM8 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.
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分子量
- 80 kDa
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基因ID
- 101
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UniProt
- P78325
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途径
- Activation of Innate immune Response, M Phase
抗原
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