HNRNPK 抗体 (AA 40-463)
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Quick Overview for HNRNPK 抗体 (AA 40-463) (ABIN7601650)
抗原
See all HNRNPK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-463
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原理
- Anti-hnRNP K/HNRNPK Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-hnRNP K/HNRNPK Antibody. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human hnRNP K/HNRNPK recombinant protein (Position: D40-F463).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
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别名
- HNRNPK
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背景
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Background: Heterogeneous nuclear ribonucleoprotein K (also protein K) is a protein that in humans is encoded by the HNRNPK gene. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference, it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.
Gene Full Name: heterogeneous nuclear ribonucleoprotein K
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分子量
- 60 kDa
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基因ID
- 3190
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UniProt
- P61978
抗原
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