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Recombinant HNRNPK 抗体

HNRNPK 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Monoclonal 3G7 unconjugated Recombinant Antibody
产品编号 ABIN7127548
发货至: 中国
  • 抗原 See all HNRNPK 抗体
    HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
    抗体类型
    Recombinant Antibody
    适用
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    宿主
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    克隆类型
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    单克隆
    标记
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    This HNRNPK antibody is un-conjugated
    应用范围
    • 61
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human HNRNPK
    克隆位点
    3G7
    亚型
    IgG
    Top Product
    Discover our top product HNRNPK Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
    别名
    HNRNPK (HNRNPK 产品)
    别名
    CSBP antibody, HNRPK antibody, TUNP antibody, Csbp antibody, Hnrpk antibody, hnrpk antibody, MGC75642 antibody, wu:fb37h02 antibody, wu:fi34c04 antibody, zgc:66162 antibody, KBBP antibody, NOVA antibody, heterogeneous nuclear ribonucleoprotein K antibody, heterogeneous nuclear ribonucleoprotein K S homeolog antibody, heterogeneous nuclear ribonucleoprotein k antibody, HNRNPK antibody, Hnrnpk antibody, hnrnpk.S antibody, hnrnpk antibody, LOC5565718 antibody, CpipJ_CPIJ000130 antibody, NGK_p0004 antibody
    背景

    Background: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.

    Aliases: Heterogeneous nuclear ribonucleoprotein K, hnRNP K, Transformation up-regulated nuclear protein, TUNP, HNRNPK, HNRPK

    UniProt
    P61978
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