HNRNPK 抗体 (AA 40-463)
Quick Overview for HNRNPK 抗体 (AA 40-463) (ABIN7601650)
抗原
See all HNRNPK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-463
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原理
- Anti-hnRNP K/HNRNPK Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-hnRNP K/HNRNPK Antibody Picoband® (ABIN7601650). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human hnRNP K/HNRNPK recombinant protein (Position: D40-F463).
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亚型
- IgG
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anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-280) antibody
HNRNPK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) antibodyHNRNPK 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) antibodyHNRNPK 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Monoclonal 3G7 unconjugated Recombinant Antibody
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, Cow, 非洲爪蟾, Hamster WB, IHC, ELISA, IF, IP, ICC, FACS, ChIP 宿主: 小鼠 Monoclonal 3C2 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-463) antibodyHNRNPK 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (pSer284) antibodyHNRNPK 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 371-420) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 斑马鱼, 小鸡, 豚鼠, 山羊, 马, 猴, 非洲爪蟾, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 小鸡, 豚鼠, 山羊, 马, 猴, 非洲爪蟾, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (C-Term) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Au, P. Y. B., Goedhart, C., Ferguson, M., Breckpot, J., Devriendt, K., Wierenga, K., Fanning, E., Grange, D. K., Graham, G. E., Galarreta, C., Jones, M. C., Kini, U., Stewart, H., Parboosingh, J. S., Kline, A. D., Innes, A. M., Care for Rare Canada Consortium. Phenotypic spectrum of Au-Kline syndrome: a report of six new cases and review of the literature. Europ. J. Hum. Genet. 26: 1272-1281, 2018. 2. Au, P. Y. B., You, J., Caluseriu, O., Schwartzentruber, J., Majewski, J., Bernier, F. P., Ferguson, M., Care for Rare Canada Consortium, Valle, D., Parboosingh, J. S., Sobreira, N., Innes, A. M., Kline, A. D. GeneMatcher aids in the identification of a new malformation syndrome with intellectual disability, unique facial dysmorphisms, and skeletal and connective tissue abnormalities caused by de novo variants in HNRNPK. Hum. Mutat. 36: 1009-1014, 2015. 3. Dejgaard, K., Leffers, H., Rasmussen, H. H., Madsen, P., Kruse, T. A., Gesser, B., Nielsen, H., Celis, J. E. Identification, molecular cloning, expression and chromosome mapping of a family of transformation upregulated hnRNP-K proteins derived by alternative splicing. J. Molec. Biol. 236: 33-48, 1994. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
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别名
- HNRNPK
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背景
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Synonyms: Protein CBFA2T1, Cyclin-D-related protein, Eight twenty one protein, Protein ETO, Protein MTG8, Zinc finger MYND domain-containing protein 2, RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Tissue Specificity: Most abundantly expressed in brain. Lower levels in lung, heart, testis and ovary.
Background: Heterogeneous nuclear ribonucleoprotein K (also protein K) is a protein that in humans is encoded by the HNRNPK gene. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference, it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.
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分子量
- 60 kDa
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基因ID
- 3190
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UniProt
- P61978
抗原
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