NOS2 抗体 (AA 40-1099)
Quick Overview for NOS2 抗体 (AA 40-1099) (ABIN7601635)
抗原
See all NOS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-1099
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原理
- Anti-iNOS/Nos2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-iNOS/Nos2 Antibody Picoband® (ABIN7601635). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse iNOS/Nos2 recombinant protein (Position: I40-L1099).
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亚型
- IgG
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anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 14-100) antibody
NOS2 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) antibodyNOS2 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4E5 unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 43-213) antibodyNOS2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 518-694) antibodyNOS2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (Thr177) antibodyNOS2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (C-Term) antibodyNOS2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 500-730) antibodyNOS2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 830-860) antibodyNOS2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB18210 unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) antibodyNOS2 适用: 人, 小鼠, 大鼠, 小鸡, 犬 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 533-696) antibodyNOS2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Chartrain, N. A., Geller, D. A., Koty, P. P., Sitrin, N. F., Nussler, A. K., Hoffman, E. P., Billiar, T. R., Hutchinson, N. I., Mudgett, J. S. Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene. J. Biol. Chem. 269: 6765-6772, 1994. 2. Diefenbach, A., Schindler, H., Rollinghoff, M., Yokoyama, W. M., Bogdan, C. Requirement for type 2 NO synthase for IL-12 signaling in innate immunity. Science 284: 951-955, 1999. 3. Hobbs, M. R., Udhayakumar, V., Levesque, M. C., Booth, J., Roberts, J. M., Tkachuk, A. N., Pole, A., Coon, H., Kariuki, S., Nahlen, B. L., Mwaikambo, E. D., Lai, A. L., Granger, D. L., Anstey, N. M., Weinberg, J. B. A new NOS2 promoter polymorphism associated with increased nitric oxide production and protection from severe malaria in Tanzanian and Kenyan children. Lancet 360: 1468-1475, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
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别名
- Nos2
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背景
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Synonyms: Nitric oxide synthase, inducible,1.14.13.39,Hepatocyte NOS,HEP-NOS,Inducible NO synthase,Inducible NOS,iNOS,N
Tissue Specificity: Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.
Background: Nitric oxide synthase, inducible is an enzyme that in humans is encoded by the NOS2 gene. Nitric oxide (NO) is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter, it is implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. Three different NOS isoforms have been identified which fall into two distinct types, constitutive and inducible. The inducible NOS (iNOS) isoform is expressed in a variety of cell types and tissues in response to inflammatory agents and cytokines. The human iNOS (NOS2) gene is approximately 37 kb in length and consists of 26 exons and 25 introns. NOS2-derived NO is a prerequisite for cytokine signaling and function in innate immunity.
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分子量
- 130 kDa
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基因ID
- 18126
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UniProt
- P29477
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途径
- Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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