FLNB 抗体 (AA 397-701)
Quick Overview for FLNB 抗体 (AA 397-701) (ABIN7601607)
抗原
See all FLNB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 397-701
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原理
- Anti-Filamin B/FLNB Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Filamin B/FLNB Antibody Picoband® (ABIN7601607). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Filamin B/FLNB recombinant protein (Position: Q397-D701).
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亚型
- IgG
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anti-Filamin B, beta (FLNB) antibody
FLNB 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 1686-1785) antibodyFLNB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (N-Term) antibodyKO Validated FLNB 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 30-239) antibodyFLNB 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 1-237) antibodyFLNB 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 1551-1650) antibodyFLNB 适用: 人 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 2061-2193) antibodyFLNB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 2061-2193) antibodyFLNB 适用: 人 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 163-196) antibodyFLNB 适用: 人 WB 宿主: 兔 Polyclonal RB54051 unconjugated
anti-Filamin B, beta (FLNB) (AA 288-322) antibodyFLNB 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB54052 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bicknell, L. S., Farrington-Rock, C., Shafeghati, Y., Rump, P., Alanay, Y., Alembik, Y., Al-Madani, N., Firth, H., Karimi-Nejad, M. H., Kim, C. A., Leask, K., Maisenbacher, M., and 14 others. A molecular and clinical study of Larsen syndrome caused by mutations in FLNB. J. Med. Genet. 44: 89-98, 2007. 2. Bicknell, L. S., Morgan, T., Bonafe, L., Wessels, M. W., Bialer, M. G., Willems, P. J., Cohn, D. H., Krakow, D., Robertson, S. P. Mutations in FLNB cause boomerang dysplasia. J. Med. Genet. 42: e43, 2005. Note: Electronic Article. 3. Biesecker, L. G. Phenotype matters. Nature Genet. 36: 323-324, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- FLNB (Filamin B, beta (FLNB))
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别名
- FLNB
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背景
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Synonyms: Tumor necrosis factor ligand superfamily member 4, OX40 ligand, OX40L, CD252, Tnfsf4, Ox40l, Txgp1l
Tissue Specificity: Macrophages, peripheral blood leukocytes, lung, spleen and liver.
Background: Filamin B, beta (FLNB), also known as Filamin B, beta (truncated actin binding protein 278 homolog), is a cytoplasmic protein which in humans is encoded by the FLNB gene. This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
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分子量
- 278 kDa
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基因ID
- 2317
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UniProt
- O75369
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途径
- Maintenance of Protein Location
抗原
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