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FLNB 抗体 (N-Term)

KO Validated FLNB 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854971
发货至: 中国
  • 抗原 See all FLNB 抗体
    FLNB (Filamin B, beta (FLNB))
    抗原表位
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 44
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 39
    • 4
    • 1
    克隆类型
    • 41
    • 3
    多克隆
    标记
    • 26
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FLNB antibody is un-conjugated
    应用范围
    • 41
    • 13
    • 13
    • 12
    • 10
    • 8
    • 7
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to Filamin B (filamin B, beta)
    Filamin B antibody [N1], N-term
    纯化方法
    Affinity purified by Protein A.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the N-terminus region of human Filamin B. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product FLNB Primary Antibody
  • 应用备注
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: U87-MG , NIH-3T3 , 293T , A431 , HeLa , HepG2

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    10 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Artym, Swatkoski, Matsumoto, Campbell, Petrie, Dimitriadis, Li, Mueller, Bugge, Gucek, Yamada: "Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network." in: The Journal of cell biology, Vol. 208, Issue 3, pp. 331-50, (2015) (PubMed).

  • 抗原
    FLNB (Filamin B, beta (FLNB))
    别名
    filamin B (FLNB 产品)
    别名
    ABP-278 antibody, ABP-280 antibody, AOI antibody, FH1 antibody, FLN-B antibody, FLN1L antibody, LRS1 antibody, SCT antibody, TABP antibody, TAP antibody, AL024016 antibody, filamin B antibody, filamin, beta antibody, FLNB antibody, Flnb antibody
    背景
    This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

    Cellular Localization: Isoform 1: Cytoplasm , cell cortex , Cytoplasm , cytoskeleton , myofibril , sarcomere , Z-disk , Isoform 2: Cytoplasm , Isoform 3: Cytoplasm , Isoform 6: Cytoplasm
    分子量
    278 kDa
    基因ID
    2317
    UniProt
    O75369
    途径
    Maintenance of Protein Location
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