FOXC1 抗体 (AA 392-554)
Quick Overview for FOXC1 抗体 (AA 392-554) (ABIN7601591)
抗原
See all FOXC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 392-554
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原理
- Anti-FOXC1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-FOXC1 Antibody Picoband® (ABIN7601591). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FOXC1 recombinant protein (Position: T392-F554).
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亚型
- IgG
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anti-Forkhead Box C1 (FOXC1) (C-Term) antibody
Verified FOXC1 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) antibodyFOXC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (AA 1-79) antibodyFOXC1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (Center) antibodyFOXC1 适用: 人, 小鼠, 大鼠, 小鸡 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (AA 101-200) antibodyFOXC1 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (AA 62-186) antibodyFOXC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (Internal Region) antibodyVerified FOXC1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (N-Term) antibodyFOXC1 适用: 人, 小鼠, 斑马鱼, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (AA 464-553) antibodyFOXC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D11 unconjugated
anti-Forkhead Box C1 (FOXC1) (AA 406-455) antibodyFOXC1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Pierrou S, Hellqvist M, Samuelsson L, Enerbäck S, Carlsson P (October 1994). "Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending". The EMBO Journal. 13 (20): 5002-12. 2. Nishimura DY, Swiderski RE, Alward WL, Searby CC, Patil SR, Bennet SR, Kanis AB, Gastier JM, Stone EM, Sheffield VC (June 1998). "The forkhead transcription factor gene FKHL7 is responsible for glaucoma phenotypes which map to 6p25". Nature Genetics. 19 (2): 140-7. 3. Kume T, Jiang H, Topczewska JM, Hogan BL (September 2001). "The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis". Genes & Development. 15 (18): 2470-82. doi:10.1101/gad.907301. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- FOXC1 (Forkhead Box C1 (FOXC1))
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别名
- FOXC1
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背景
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Synonyms: Forkhead box protein C1, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3, FREAC-3, FOXC1, FKHL7, FREAC3
Tissue Specificity: Expressed in keratinocytes of epidermis and hair follicle (PubMed:27907090). Expressed strongly in microvascular invasion (MVI) formation, basal-like breast cancer (BLBC) and hepatocellular tumors (PubMed:20406990, PubMed:22991501). Expressed in breast cancers (at protein level) (PubMed:26565916). Expressed in hematopoietic cells (PubMed:8499623).
Background: Forkhead box C1, also known as?FOXC1, is a?protein?which in humans is encoded by the?FOXC1?gene. It is mapped to 6p25.3. This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined, however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.
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分子量
- 75 kDa
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基因ID
- 2296
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UniProt
- Q12948
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途径
- Chromatin Binding, Glycosaminoglycan Metabolic Process
抗原
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