PFKM 抗体 (AA 39-780)
Quick Overview for PFKM 抗体 (AA 39-780) (ABIN7601586)
抗原
See all PFKM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 39-780
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原理
- Anti-PFKM Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-PFKM Antibody Picoband® (ABIN7600170). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PFKM recombinant protein (Position: R39-V780). Human PFKM shares 97.7% and 96.8% amino acid (aa) sequence identity with mouse and rat PFKM, respectively.
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亚型
- IgG
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anti-phosphofructokinase, Muscle (PFKM) (AA 2-390) antibody
PFKM 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphofructokinase, Muscle (PFKM) (AA 501-780) antibodyPFKM 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphofructokinase, Muscle (PFKM) (AA 166-334) antibodyPFKM 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphofructokinase, Muscle (PFKM) (AA 1-780) antibodyPFKM 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-phosphofructokinase, Muscle (PFKM) (AA 681-780) antibodyPFKM 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D1 unconjugated
anti-phosphofructokinase, Muscle (PFKM) (AA 746-776), (C-Term) antibodyPFKM 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB3908 unconjugated
anti-phosphofructokinase, Muscle (PFKM) (AA 1-780) antibodyPFKM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-phosphofructokinase, Muscle (PFKM) (N-Term) antibodyKO Validated PFKM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphofructokinase, Muscle (PFKM) antibodyPFKM 适用: 兔 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-phosphofructokinase, Muscle (PFKM) (AA 1-253) antibodyPFKM 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ashley, P. L., Price, E. R., Lebo, R. V., Cox, D. R. An expressed phosphofructokinase gene (PFKX) maps to human chromosome 12 and mouse chromosome 15. (Abstract) Cytogenet. Cell Genet. 46: 573 only, 1987. 2. Bruno, C., Minetti, C., Shanske, S., Morreale, G., Bado, M., Cordone, G., DiMauro, S. Combined defects of muscle phosphofructokinase and AMP deaminase in a child with myoglobinuria. Neurology 50: 296-298, 1998. 3. Hamaguchi, T., Nakajima, H., Noguchi, T., Nakagawa, C., Kuwajima, M., Kono, N., Tarui, S., Matsuzawa, Y. Novel missense mutation (W686C) of the phosphofructokinase-M gene in a Japanese patient with a mild form of glycogenosis VII. Hum. Mutat. 8: 273-275, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PFKM (phosphofructokinase, Muscle (PFKM))
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别名
- PFKM
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: 6-phosphofructokinase, muscle type is an enzyme that in humans is encoded by the PFKM gene on chromosome 12. Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
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分子量
- 85 kDa
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基因ID
- 5213
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UniProt
- P08237
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途径
- Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effect
抗原
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