AKAP12 抗体 (AA 387-1620)
Quick Overview for AKAP12 抗体 (AA 387-1620) (ABIN7601563)
抗原
See all AKAP12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 387-1620
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原理
- Anti-AKAP12 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-AKAP12 Antibody Picoband® (ABIN7601563). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse AKAP12 recombinant protein (Position: E387-H1620).
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亚型
- IgG
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anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 1485-1782) antibody
AKAP12 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 701-900) antibodyAKAP12 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IHC (fro), FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 1675-1782) antibodyAKAP12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (C-Term) antibodyAKAP12 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) antibodyAKAP12 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) antibodyAKAP12 适用: 大鼠 WB 宿主: 绵羊 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 1719-1782) antibodyAKAP12 适用: 人 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (C-Term) antibodyAKAP12 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 301-350) antibodyAKAP12 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 1639-1652), (Intracellular) antibodyAKAP12 适用: 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Mouse
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Gordon, T., Grove, B., Loftus, J. C., O'Toole, T., McMillan, R., Lindstrom, J., Ginsberg, M. H. Molecular cloning and preliminary characterization of a novel cytoplasmic antigen recognized by myasthenia gravis sera. J. Clin. Invest. 90: 992-999, 1992. 2. Lee, S.-W., Kim, W. J., Choi, Y. K., Song, H. S., Son, M. J., Gelman, I. H., Kim, Y.-J., Kim, K.-W. SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier. Nature Med. 9: 900-906, 2003. 3. Nauert, J. B., Klauck, T. M., Langeberg, L. K., Scott, J. D. Gravin, an autoantigen recognized by serum from myasthenia gravis patients, is a kinase scaffold protein. Curr. Biol. 7: 52-62, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
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别名
- Akap12
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背景
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Synonyms: Tumor necrosis factor receptor superfamily member 14,Herpes virus entry mediator A,Herpesvirus entry mediator A,HveA,Tumor necrosis factor receptor-like 2,TR2,CD270,TNFRSF14,HVEA, HVEM,UNQ329/PRO509,
Tissue Specificity: Widely expressed, with the highest expression in lung, spleen and thymus.
Background: A-kinase anchor protein 12, aka AKAP250, is an enzyme that in humans is encoded by the AKAP12 gene. The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinase A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
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分子量
- 300 kDa
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基因ID
- 83397
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途径
- cAMP Metabolic Process
抗原
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