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AKAP12 抗体 (AA 301-350)

The 兔 多克隆 anti-AKAP12 antibody (ABIN1533824) specifically detects AKAP12 in IHC, ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1533824
发货至: 中国
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Quick Overview for AKAP12 抗体 (AA 301-350) (ABIN1533824)

抗原

See all AKAP12 抗体
AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

适用

  • 20
  • 17
  • 17
  • 1
人, 小鼠, 大鼠

宿主

  • 32
  • 2
  • 2
  • 1
兔

克隆类型

  • 36
  • 1
多克隆

标记

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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This AKAP12 antibody is un-conjugated

应用范围

  • 25
  • 21
  • 17
  • 17
  • 14
  • 12
  • 4
  • 4
  • 2
  • 1
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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 13
    • 4
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    • 1
    • 1
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    AA 301-350

    原理

    AKAP 250 Antibody

    特异性

    AKAP 250 Polyclonal Antibody detects endogenous levels of AKAP 250 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human AKAP12. AA range:301-350

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

    别名

    AKAP12

    背景

    Synonyms: AKAP12, AKAP250, A-kinase anchor protein 12, AKAP-12, A-kinase anchor protein 250 kDa, AKAP 250, Gravin, Myasthenia gravis autoantigen

    Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell.This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

    Gene Name: AKAP12

    Protein Name: A-kinase anchor protein 12

    分子量

    191 kDa

    基因ID

    9590

    OMIM

    604698

    UniProt

    Q02952

    途径

    cAMP Metabolic Process
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