SP1 抗体 (AA 384-603)
Quick Overview for SP1 抗体 (AA 384-603) (ABIN7601559)
抗原
See all SP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 384-603
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原理
- Anti-SP1 Antibody Picoband® (monoclonal, 3C4C3)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SP1 Antibody Picoband® (monoclonal, 3C4C3) (ABIN7601559). Tested in Flow Cytometry, IF, ICC, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human SP1 recombinant protein (Position: Q384-A603).
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亚型
- IgG1
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anti-Sp1 Transcription Factor (SP1) (pThr453) antibody
SP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (C-Term) antibodySP1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibodySP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4H6 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 522-618) antibodySP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B11 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibodySP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Sp1 Transcription Factor (SP1) antibodySP1 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-199) antibodySP1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4H6 unconjugated
anti-Sp1 Transcription Factor (SP1) (pThr739) antibodySP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 420-620) antibodySP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 677-707), (C-Term) antibodySP1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB17350 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Gaynor, R. B., Shieh, B.-H., Klisak, I., Sparkes, R. S., Lusis, A. J.Localization of the transcription factor SP1 gene to human chromosome 12q12-q13.2.Cytogenet. Cell Genet. 64: 210-212, 1993. 2. Matera, A. G., Ward, D. C.Localization of the human Sp1 transcription factor gene to 12q13 by fluorescence in situ hybridization.Genomics 17: 793-794, 1993. 3. Wimmer, E. A., Jackle, H., Pfeifle, C., Cohen, S. M.A Drosophila homologue of human Sp1 is a head-specific segmentation gene.Nature 366: 690-694, 1993.Wimmer, E. A., Jackle, H., Pfeifle, C., Cohen, S. M.A Drosophila homologue of human Sp1 is a head-specific segmentation gene.Nature 366: 690-694, 1993. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SP1 (Sp1 Transcription Factor (SP1))
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别名
- SP1
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背景
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Synonyms: Interleukin-6, IL-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IL6, IFNB2
Tissue Specificity: Ubiquituous. Expressed in platelets.
Background: Transcription factor Sp1, also known as specificity protein 1* is a protein that in humans is encoded by the SP1 gene. The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.
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分子量
- 90 kDa
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基因ID
- 6667
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UniProt
- P08047
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途径
- Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
抗原
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