WHSC2 抗体 (AA 38-482)
Quick Overview for WHSC2 抗体 (AA 38-482) (ABIN7601547)
抗原
See all WHSC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 38-482
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原理
- Anti-NELFA Antibody Picoband®
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产品特性
- Anti-NELFA Antibody Picoband® (ABIN7601547). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NELFA recombinant protein (Position: I38-L482). Human NELFA shares 94.6% amino acid (aa) sequence identity with mouse NELFA.
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anti-Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2) (AA 280-511) antibody
WHSC2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 6B11H8 unconjugated
anti-Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2) (AA 280-511) antibodyWHSC2 适用: 人, 大鼠 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2) (AA 1-528) antibodyWHSC2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2) (AA 429-527) antibodyWHSC2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2) (AA 280-511) antibodyWHSC2 适用: 人 WB, ELISA, IF, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 6B11H8 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Narita, T., Yamaguchi, Y., Yano, K., Sugimoto, S., Chanarat, S., Wada, T., Kim, D., Hasegawa, J., Omori, M., Inukai, N., Endoh, M., Yamada, T., Handa, H. Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex. Molec. Cell. Biol. 23: 1863-1873, 2003. 2. Narita, T., Yung, T. M. C., Yamamoto, J., Tsuboi, Y., Tanabe, H., Tanaka, K., Yamaguchi, Y., Handa, H. NELF interacts with CBC and participates in 3-prime end processing of replication-dependent histone mRNAs. Molec. Cell 26: 349-365, 2007. 3. Wright, T. J., Costa, J. L., Naranjo, C., Francis-West, P., Altherr, M. R. Comparative analysis of a novel gene from the Wolf-Hirschhorn/Pitt-Rogers-Danks syndrome critical region. Genomics 59: 203-212, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
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别名
- NELFA
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背景
- This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
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分子量
- 57 kDa
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基因ID
- 7469
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UniProt
- Q9H3P2
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途径
- Chromatin Binding
抗原
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