KDM4A 抗体 (AA 379-1064)
Quick Overview for KDM4A 抗体 (AA 379-1064) (ABIN7601534)
抗原
See all KDM4A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 379-1064
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原理
- Anti-JHDM3A/JMJD2A/KDM4A Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-JHDM3A/JMJD2A/KDM4A Antibody Picoband® (ABIN7601534). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human JHDM3A/JMJD2A/KDM4A recombinant protein (Position: D379-E1064).
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 141-310) antibody
KDM4A 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 932-1057) antibodyKDM4A 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6E10G4 unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 585-815) antibodyKDM4A 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) antibodyKDM4A 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 5H1 unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 127-364) antibodyKDM4A 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) antibodyKDM4A 适用: 人 DB, ICC 宿主: 小鼠 Monoclonal 3559D5a unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (Center) antibodyKDM4A 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, Z., Zang, J., Whetstine, J., Hong, X., Davrazou, F., Kutateladze, T. G., Simpson, M., Mao, Q., Pan, C.-H., Dai, S., Hagman, J., Hansen, K., Shi, Y., Zhang, G. Structural insights into histone demethylation by JMJD2 family members. Cell 125: 691-702, 2006. 2. Ishikawa, K., Nagase, T., Suyama, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 5: 169-176, 1998. 3. Katoh, M., Katoh, M. Identification and characterization of JMJD2 family genes in silico. Int. J. Oncol. 24: 1623-1628, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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别名
- KDM4A
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背景
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Synonyms: gasdermin D, gasdermin-D
Tissue Specificity: Brain, placental, and gut tissues.
Background: Lysine-specific demethylase 4A is an enzyme that in humans is encoded by the KDM4A gene. This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
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分子量
- 150 kDa
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基因ID
- 9682
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UniProt
- O75164
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途径
- Warburg Effect
抗原
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