HTR2C 抗体 (AA 372-458)
Quick Overview for HTR2C 抗体 (AA 372-458) (ABIN7601526)
抗原
See all HTR2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 372-458
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原理
- Anti-5-HT2C Receptor/HTR2C Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-5-HT2C Receptor/HTR2C Antibody Picoband® (ABIN7601526). Tested in ELISA, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human 5-HT2C Receptor/HTR2C recombinant protein (Position: N372-V458).
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亚型
- IgG
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anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (N-Term) antibody
HTR2C 适用: 人, 小鼠, 大鼠, Pig, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 387-446) antibodyHTR2C 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (Internal Region) antibodyHTR2C 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) antibodyHTR2C 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 9H8 unconjugated Recombinant Antibody
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (Cytoplasmic Domain) antibodyHTR2C 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 1-52) antibodyHTR2C 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (C-Term) antibodyHTR2C 适用: 人 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 311-410) antibodyHTR2C 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 274-308) antibodyHTR2C 适用: 人 WB 宿主: 兔 Polyclonal RB52766 unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 1-52) antibodyHTR2C 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Brennan, T. J., Seeley, W. W., Kilgard, M., Schreiner, C. E., Tecott, L. H. Sound-induced seizures in serotonin 5-HT-2C receptor mutant mice. Nature Genet. 16: 387-390, 1997. 2. Di Narzo, A. F., Kozlenkov, A., Roussos, P., Hao, K., Hurd, Y., Lewis, D. A., Sibille, E., Siever, L. J., Koonin, E., Dracheva, S. A unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicide. Hum. Molec. Genet. 23: 4801-4813, 2014. 3. Doe, C. M., Relkovic, D., Garfield, A. S., Dalley, J. W., Theobald, D. E. H., Humby, T., Wilkinson, L. S., Isles, A. R. Loss of imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT(2C)R-mediated behaviour. Hum. Molec. Genet. 18: 2140-2148, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
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别名
- HTR2C
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背景
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Synonyms: Neutrophil cytosol factor 1, NCF-1, 47 kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, NCF-47K, Neutrophil NADPH oxidase factor 1, Nox organizer 2, Nox-organizing protein 2, SH3 and PX domain-containing protein 1A, p47-phox, NCF1, NOXO2, SH3PXD1A
Tissue Specificity: Detected in peripheral blood monocytes and neutrophils (at protein level).
Background: This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants.
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分子量
- 75 kDa
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基因ID
- 3358
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UniProt
- P28335
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途径
- Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
抗原
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