PNLIP 抗体 (AA 36-404)
Quick Overview for PNLIP 抗体 (AA 36-404) (ABIN7601474)
抗原
See all PNLIP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 36-404
-
原理
- Anti-Pancreatic Lipase/PNLIP Antibody Picoband®
-
交叉反应 (详细)
- No cross reactivity with other proteins.
-
产品特性
- Anti-Pancreatic Lipase/PNLIP Antibody Picoband® (ABIN7601474). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Pancreatic Lipase/PNLIP recombinant protein (Position: I36-D404). Human PNLIP shares 78.7% amino acid (aa) sequence identity with mouse and rat PNLIP.
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot, 0.5-1 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Behar, D. M., Basel-Vanagaite, L., Glaser, F., Kaplan, M., Tzur, S., Magal, N., Eidlitz-Markus, T., Haimi-Cohen, Y., Sarig, G., Bormans, C., Shohat, M., Zeharia, A. Identification of a novel mutation in the PNLIP gene in two brothers with congenital pancreatic lipase deficiency. J. Lipid Res. 55: 307-312, 2014. 2. Davis, R. C., Diep, A., Hunziker, W., Klisak, I., Mohandas, T., Schotz, M. C., Sparkes, R. S., Lusis, A. J. Assignment of human pancreatic lipase gene (PNLIP) to chromosome 10q24-q26. Genomics 11: 1164-1166, 1991. 3. Lowe, M. E., Rosenblum, J. L., Strauss, A. W. Cloning and characterization of human pancreatic lipase cDNA. J. Biol. Chem. 264: 20042-20048, 1989. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- PNLIP (Pancreatic Lipase (PNLIP))
-
别名
- PNLIP
-
背景
-
Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: This gene encodes a member of the lipase family of proteins. The encoded enzyme is secreted by the pancreas and hydrolyzes triglycerides in the small intestine, and is essential for the efficient digestion of dietary fats. Inhibition of the encoded enzyme may prevent high-fat diet-induced obesity in mice and result in weight loss in human patients with obesity. Mutations in this gene cause congenital pancreatic lipase deficiency, a rare disorder characterized by steatorrhea.
-
分子量
- 51 kDa
-
基因ID
- 5406
-
UniProt
- P16233
抗原
-