DMC1 抗体 (AA 36-283)
Quick Overview for DMC1 抗体 (AA 36-283) (ABIN7601468)
抗原
See all DMC1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 36-283
-
原理
- Anti-DMC1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-DMC1 Antibody Picoband® (ABIN7601468). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human DMC1 recombinant protein (Position: D36-D283).
-
亚型
- IgG
-
-
anti-DNA Meiotic Recombinase 1 (DMC1) (AA 237-339) antibody
DMC1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4A10 unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (AA 5-153) antibodyDMC1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) antibodyDMC1 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF, StM 宿主: 小鼠 Monoclonal 2H12-4 unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (Center) antibodyDMC1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) antibodyDMC1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (AA 237-339) antibodyDMC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E2 unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (Internal Region) antibodyDMC1 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (AA 1-260) antibodyDMC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (AA 1-30), (N-Term) antibodyDMC1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23872 unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (AA 1-30), (N-Term) antibodyDMC1 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cloud, V., Chan, Y.-L., Grubb, J., Budke, B., Bishop, D. K. Rad51 is an accessory factor for Dmc1-mediated joint molecule formation during meiosis. Science 337: 1222-1225, 2012. 2. Habu, T., Taki, T., West, A., Nishimune, Y., Morita, T. The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon-skipped transcript in meiosis. Nucleic Acids Res. 24: 470-477, 1996. 3. He, W.-B., Tu, C.-F., Liu, Q., Meng, L.-L., Yuan, S.-M., Luo, A.-X., He, F.-S., Shen, J., Li, W., Du, J., Zhong, C.-G., Lu, G.-X., Lin, G., Fan, L.-Q., Tan, Y.-Q. DMC1 mutation that causes human non-obstructive azoospermia and premature ovarian insufficiency identified by whole-exome sequencing. J. Med. Genet. 55: 198-204, 2018. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- DMC1 (DNA Meiotic Recombinase 1 (DMC1))
-
别名
- DMC1
-
背景
-
Synonyms: Aldo-keto reductase family 1 member B10,1.1.1.-,ARL-1,Aldose reductase-like,Aldose reductase-related protein,ARP,hARP,Small intestine reductase,SI reductase,AKR1B10,AKR1B11,
Tissue Specificity: Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
Background: Meiotic recombination protein DMC1/LIM15 homolog is a protein that in humans is encoded by the DMC1 gene. This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants.
-
分子量
- 37 kDa
-
基因ID
- 11144
-
UniProt
- Q14565
抗原
-
