CD55 抗体 (AA 35-347)
Quick Overview for CD55 抗体 (AA 35-347) (ABIN7601423)
抗原
See all CD55 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 35-347
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原理
- Anti-CD55 Antibody Picoband® (monoclonal, 9F3A1)
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-CD55 Antibody Picoband® (monoclonal, 9F3A1) (ABIN7601423). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CD55 recombinant protein (Position: D35-K347). Human CD55 shares 49.1% amino acid (aa) sequence identity with mouse CD55.
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亚型
- IgG2b
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
1. Medof ME, Lublin DM, Holers VM, Ayers DJ, Getty RR, Leykam JF, Atkinson JP, Tykocinski ML (April 1987). "Cloning and characterization of cDNAs encoding the complete sequence of decay-accelerating factor of human complement"". Proc. Natl. Acad. Sci. U.S.A. 84 (7): 2007-11. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CD55 (Complement Decay-Accelerating Factor (CD55))
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别名
- CD55
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背景
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Synonyms: ATP dependent helicase RENT1 antibody, ATP-dependent helicase RENT1 antibody, Delta helicase antibody, FLJ43809 antibody, FLJ46894 antibody, HUPF 1 antibody, hUpf1 antibody, KIAA0221 antibody, Nonsense mRNA reducing factor 1 antibody, NORF 1 antibody, NORF1 antibody, pNORF 1 antibody, pNORF1 antibody, Regulator of nonsense transcripts 1 antibody, RENT 1 antibody, RENT1 antibody, RENT1_HUMAN antibody, Smg 2 antibody, Smg 2 homolog nonsense mediated mRNA decay factor antibody, UP Frameshift 1 antibody, Up frameshift mutation 1 homolog (S. cerevisiae) antibody, Up frameshift mutation 1 homolog antibody, Up frameshift suppressor 1 homolog antibody, Up-frameshift suppressor 1 homolog antibody, UPF 1 antibody, UPF 1 regulator of nonsense transcripts homolog antibody, upf1 antibody, UPF1 regulator of nonsense transcripts homolog antibody, Yeast Upf1p homolog antibody
Tissue Specificity: Ubiquitous.
Background: Complement decay-accelerating factor, also known as CD55 or DAF, is a protein that, in humans, is encoded by the CD55 gene. This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins.
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分子量
- 70-75 kDa
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基因ID
- 1604
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UniProt
- P08174
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途径
- Complement System, Regulation of Leukocyte Mediated Immunity
抗原
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