SUFUH 抗体 (AA 34-484)
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Quick Overview for SUFUH 抗体 (AA 34-484) (ABIN7601394)
抗原
See all SUFUH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 34-484
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原理
- Anti-SUFU Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-SUFU Antibody (ABIN7601394). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SUFU recombinant protein (Position: L34-H484).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SUFUH (Suppressor of Fused Homolog (SUFUH))
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别名
- SUFU
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背景
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Synonyms: Suppressor of fused homolog, SUFUH, SUFU, UNQ650, PRO1280
Tissue Specificity: Detected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle.
Background: Suppressor of fused homolog is a protein that in humans is encoded by the SUFU gene. It is mapped to 10q24.32. The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
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分子量
- 54 kDa
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基因ID
- 51684
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途径
- Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
抗原
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