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CTBP2 抗体 (AA 321-445)

This anti-CTBP2 antibody is a 小鼠 单克隆 antibody detecting CTBP2 in WB, IHC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601326
发货至: 中国

Quick Overview for CTBP2 抗体 (AA 321-445) (ABIN7601326)

抗原

See all CTBP2 抗体
CTBP2 (C-terminal Binding Protein 2 (CTBP2))

适用

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人, 小鼠, 大鼠

宿主

  • 45
  • 9
小鼠

克隆类型

  • 47
  • 7
单克隆

标记

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This CTBP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

7F3E1
  • 抗原表位

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    AA 321-445

    原理

    Anti-CTBP2 Antibody Picoband® (monoclonal, 7F3E1)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-CTBP2 Antibody Picoband® (monoclonal, 7F3E1) (ABIN7601326). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CTBP2 recombinant protein (Position: H321-Q445). human CTBP2 shares 99.2% and 98.4% amino acid (aa) sequence identity with mouse and rat CTBP2, respectively.

    亚型

    IgG2a
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Furusawa, T., Moribe, H., Kondoh, H., Higashi, Y.Identification of CtBP1 and CTBP2 as corepressors of zinc finger-homeodomain factor delta-EF1.Molec. Cell. Biol. 19: 8581-8590, 1999. 2. Thomas, G., Jacobs, K. B., Yeager, M., Kraft, P., Wacholder, S., Orr, N., Yu, K., Chatterjee, N., Welch, R., Hutchinson, A., Crenshaw, A., Cancel-Tassin, G., and 27 others.Multiple loci identified in a genome-wide association study of prostate cancer.Nature Genet. 40: 310-315, 2008. 3. Turner, J., Crossley, M.Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators.EMBO J. 17: 5129-5140, 1998.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    CTBP2 (C-terminal Binding Protein 2 (CTBP2))

    别名

    CTBP2

    背景

    Synonyms: CMT2L, CRYAC, DHMN 2, DHMN2, E2IG1, H11, HMN 2, HMN2, HMN2A, HSB8, HSPB 8, HspB8

    Tissue Specificity: Predominantly expressed in skeletal muscle and heart.

    Background: The E1a region of group C adenoviruses encodes 2 nearly identical proteins that are largely responsible for the oncogenic properties of adenoviruses. The CTBP1 protein binds to the C-terminal half of these E1A proteins. It's predicted that CTBP2 is a 445-amino acid protein and it is 72 % identical to CTBP1. The CTBP2 gene is mapped to chromosome 10q26.13. CTBP2 is a mammalian corepressor that targets diverse transcriptional regulators. It bounds the short medial portion of delta-EF1 containing the PLDLSL motif and it enhances transrepression activity of delta-EF1.

    分子量

    49 kDa

    基因ID

    1488

    UniProt

    P56545
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