Betacellulin 抗体 (AA 32-111)
Quick Overview for Betacellulin 抗体 (AA 32-111) (ABIN7601294)
抗原
See all Betacellulin (BTC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 32-111
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原理
- Anti-Btc Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Btc Antibody Picoband® (ABIN7601294). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Btc recombinant protein (Position: D32-Y111).
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亚型
- IgG
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anti-Betacellulin (BTC) (N-Term) antibody
BTC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Betacellulin (BTC) (AA 32-177) antibodyBTC 适用: 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Betacellulin (BTC) (AA 17-45), (N-Term) antibodyBTC 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB14431 unconjugated
anti-Betacellulin (BTC) (AA 24-54), (N-Term) antibodyBTC 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Betacellulin (BTC) (AA 1-178) antibodyBTC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Betacellulin (BTC) (AA 1-178) antibodyBTC 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Betacellulin (BTC) (Internal Region) antibodyBTC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Betacellulin (BTC) (AA 1-178) antibodyBTC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Betacellulin (BTC) antibodyBTC 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Betacellulin (BTC) antibodyBTC 适用: 人 WB, IHC, ELISA, IHC (p), Neut 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.5-1 μg/mL, Mouse
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Elbein SC, Wang X, Karim MA, et al. (2006). "Analysis of coding variants in the betacellulin gene in type 2 diabetes and insulin secretion in African American subjects.". BMC Med. Genet. 7: 62. 2. Kim HS, Shin HS, Kwak HJ, Cho CH, Lee CO, Koh GY (February 2003). "Betacellulin induces angiogenesis through activation of mitogen-activated protein kinase and phosphatidylinositol 3'-kinase in endothelial cell". FASEB J. 17 (2): 318-20. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Betacellulin (BTC)
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别名
- Btc
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背景
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Synonyms: Probetacellulin, Betacellulin, BTC, BTC
Tissue Specificity: Highly expressed in testis.
Background: Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.
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分子量
- 26 kDa
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基因ID
- 12223
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UniProt
- Q05928
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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