STK3 抗体 (AA 314-456)
Quick Overview for STK3 抗体 (AA 314-456) (ABIN7601288)
抗原
See all STK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 314-456
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原理
- Anti-STK3/MST-2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-STK3/MST-2 Antibody Picoband® (ABIN7601288). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human STK3/MST-2 recombinant protein (Position: E314-D456).
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亚型
- IgG
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anti-serine/threonine Kinase 3 (STK3) (AA 323-450) antibody
STK3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 1-491) antibodySTK3 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 311-431) antibodySTK3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F7 unconjugated
anti-serine/threonine Kinase 3 (STK3) (C-Term) antibodySTK3 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 兔, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) antibodySTK3 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) (N-Term) antibodySTK3 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 兔, 马, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 396-425), (C-Term) antibodySTK3 适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p) 宿主: 兔 Polyclonal RB1196 unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 253-350) antibodySTK3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 1-491) antibodySTK3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) antibodySTK3 适用: 人, 猴, 犬 WB, IHC 宿主: 小鼠 Monoclonal 4G10 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Monkey
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Creasy, C. L., Chernoff, J. Cloning and characterization of a member of the MST subfamily of Ste20-like kinases. Gene 167: 303-306, 1995. 2. Du, X., Wen, J., Wang, Y., Karmaus, P. W. F., Khatamian, A., Tan, H., Li, Y., Guy, C., Nguyen, T.-L. M., Dhungana, Y., Neale, G., Peng, J., Yu, J., Chi, H. Hippo/Mst signalling couples metabolic state and immune function of CD8-alpha+ dendritic cells. Nature 558: 141-145, 2018. 3. Harvey, K. F., Pfleger, C. M., Hariharan, I. K. The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell 114: 457-467, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- STK3 (serine/threonine Kinase 3 (STK3))
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别名
- STK3
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背景
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Synonyms: Cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta subunit, CD131, Csf2rb, Aic2b, Csf2rb1, Il3rb1
Tissue Specificity: Broadly expressed with higher expression in heart.
Background: Serine/threonine-protein kinase 3 is an enzyme that in humans is encoded by the STK3 gene. This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 56 kDa
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基因ID
- 6788
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UniProt
- Q13188
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途径
- Tube Formation
抗原
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