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CD226 抗体 (AA 31-333)

This anti-CD226 antibody is a 兔多克隆 antibody detecting CD226 in WB, ELISA, FACS 和 IHC. Suitable for 小鼠和大鼠.

产品编号 ABIN7601264

发货至: 中国

Quick Overview for CD226 抗体 (AA 31-333) (ABIN7601264)

抗原

See all CD226 抗体

CD226

适用

小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

61
7
7
6
6
2
2
1
1
1
1
1
1

This CD226 antibody is un-conjugated

应用范围

51
38
32
20
19
9
8
3
3
2
1
1
1
1

Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)

Discover our top product CD226 Primary Antibody

抗原表位
13

10

10

7

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 31-333

原理

Anti-CD226 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti- Antibody Picoband® (ABIN7601264). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived mouse CD226 recombinant protein (Position: E31-L333).

亚型

IgG
anti-CD226 (CD226) (AA 19-254) antibody
CD226 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-CD226 (CD226) (Tyr570) antibody
CD226 适用: 人, 小鼠, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD226 (CD226) (AA 19-254) antibody
CD226 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8D11D5 unconjugated

anti-CD226 (CD226) antibody
CD226 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal DX11 unconjugated

anti-CD226 (CD226) antibody
CD226 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-CD226 (CD226) (AA 19-247) antibody
CD226 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM95 unconjugated

anti-CD226 (CD226) (C-Term) antibody
CD226 适用: 人, 小鼠, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-CD226 (CD226) (AA 287-336), (pSer329) antibody
CD226 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD226 (CD226) antibody
CD226 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-CD226 (CD226) antibody (FITC)
GMP Grade CD226 适用: 人 FACS 宿主: 小鼠 Monoclonal 11A8 FITC

应用备注

Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Bottino, C., Castriconi, R., Pende, D., Rivera, P., Nanni, M., Carnemolla, B., Cantoni, C., Grassi, J., Marcenaro, S., Reymond, N., Vitale, M., Moretta, L., Lopez, M., Moretta, A. Identification of PVR (CD155) and nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule. J. Exp. Med. 198: 557-567, 2003. 2. Iguchi-Manaka, A., Kai, H., Yamashita, Y., Shibata, K., Tahara-Hanaoka, S., Honda, S., Yasui, T., Kikutani, H., Shibuya, K., Shibuya, A. Accelerated tumor growth in mice deficient in DNAM-1 receptor. J. Exp. Med. 205: 2959-2964, 2008. 3. Liu, J., Qian, X., Chen, Z., Xu, X., Gao, F., Zhang, S., Zhang, R., Qi, J., Gao, G. F., Yan, J. Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226. J Immun. 188: 5511-5520, 2012.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

CD226

别名

Cd226

背景

Synonyms: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform,PI3-kinase subunit beta,PI3K-beta,PI3Kbeta,PtdIns-3-kinase subunit beta,2.7.1.153,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta,PtdIns-3-kinase subunit p110-beta,p110beta,PIK3CB,PIK3C1,
Tissue Specificity: Expressed ubiquitously.
Background: DNAM 1, also known as CD226, is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.

分子量

70 kDa

基因ID

225825

UniProt

Q8K4F0

途径

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints

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