Paired Box 3 抗体 (AA 301-479)
Quick Overview for Paired Box 3 抗体 (AA 301-479) (ABIN7601236)
抗原
See all Paired Box 3 (PAX3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-479
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原理
- Anti-PAX3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PAX3 Antibody Picoband® (ABIN7601236). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PAX3 recombinant protein (Position: T301-F479).
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亚型
- IgG
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anti-Paired Box 3 (PAX3) (AA 151-250) antibody
PAX3 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 3 (PAX3) (N-Term) antibodyVerified PAX3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Paired Box 3 (PAX3) (AA 142-203) antibodyPAX3 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 7D8G7 unconjugated
anti-Paired Box 3 (PAX3) (AA 90-184) antibodyPAX3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 3 (PAX3) (Internal Region) antibodyPAX3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 3 (PAX3) (AA 98-126) antibodyPAX3 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 3 (PAX3) (AA 142-203) antibodyPAX3 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Paired Box 3 (PAX3) (AA 400-449) antibodyPAX3 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔, 斑马鱼, Bat, 猴, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 3 (PAX3) (AA 98-126), (N-Term) antibodyPAX3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21101 unconjugated
anti-Paired Box 3 (PAX3) (N-Term) antibodyPAX3 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Asher, J. H., Jr., Sommer, A., Morrell, R., Friedman, T. B. Missense mutation in the paired domain of PAX3 causes craniofacial-deafness-hand syndrome. Hum. Mutat. 7: 30-35, 1996. 2. Baldwin, C. T., Hoth, C. F., Macina, R. A., Milunsky, A. Mutations in PAX3 that cause Waardenburg syndrome type I: ten new mutations and review of the literature. Am. J. Med. Genet. 58: 115-122, 1995. 3. Barber, T. D., Barber, M. C., Cloutier, T. E., Friedman, T. B. PAX3 gene structure, alternative splicing and evolution. Gene 237: 311-319, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Paired Box 3 (PAX3)
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别名
- PAX3
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背景
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Synonyms: Transcription factor p65, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, RELA, NFKB3
Tissue Specificity: Widely expressed. Isoform 1 and isoform 3 are predominant. Isoform 4, isoform 5 and isoform 6 are expressed moderately. Isoform 8 is found at low frequency. Isoform 7, isoform 9 and isoform 10 are not expressed in adult tissues, with the exception of adult retina expressing isoform 10. Isoform 9 is faintly expressed in fetal brain, heart, lung, skeletal muscle and spleen. Fetal thymus expresses isoforms 1, 7, 9 and 10 at similar levels.
Background: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t (2,13) (q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
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分子量
- 53 kDa
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基因ID
- 5077
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UniProt
- P23760
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途径
- Sensory Perception of Sound, Tube Formation
抗原
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