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Paired Box 3 抗体 (C-Term)

The 兔 多克隆 anti-Paired Box 3 antibody (ABIN2777556) specifically detects Paired Box 3 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔 和 斑马鱼 samples.
产品编号 ABIN2777556
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Paired Box 3 抗体 (C-Term) (ABIN2777556)

抗原

See all Paired Box 3 (PAX3) 抗体
Paired Box 3 (PAX3)

适用

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人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔, 斑马鱼

宿主

  • 67
  • 18
  • 3
兔

克隆类型

  • 71
  • 17
多克隆

标记

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This Paired Box 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    原理

    PAX3 Antibody - C-terminal region

    序列

    GGVPHQPQTD YALSPLTGGL EPTTTVSASC SQRLDHMKSL DSLPTSQSYC

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against PAX3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human PAX3
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32736-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Paired Box 3 (PAX3)

    别名

    PAX3

    背景

    Background Information: PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

    Gene Name: Paired box 3

    Alternative Symbols: WS1, WS3, CDHS, HUP2

    Protein Name: Paired box protein Pax-3

    分子量

    53kDa

    基因ID

    5077

    NCBI登录号

    NP_852122

    UniProt

    P23760

    途径

    Sensory Perception of Sound, Tube Formation
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