Kallikrein 7 抗体 (AA 30-238)
Quick Overview for Kallikrein 7 抗体 (AA 30-238) (ABIN7601217)
抗原
See all Kallikrein 7 (KLK7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-238
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原理
- Anti-Klk7 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Klk7 Antibody Picoband® (ABIN7601217). Tested in ELISA, IHC, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived rat Klk7 recombinant protein (Position: K30-N238).
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亚型
- IgG
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anti-Kallikrein 7 (KLK7) (AA 1-253) antibody
KLK7 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Kallikrein 7 (KLK7) antibodyKLK7 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-707M unconjugated
anti-Kallikrein 7 (KLK7) antibodyKLK7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 7 (KLK7) (AA 23-253) antibodyKLK7 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 7 (KLK7) antibodyKLK7 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 7 (KLK7) (AA 1-253) antibodyKLK7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 7 (KLK7) (Internal Region) antibodyKLK7 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 7 (KLK7) (AA 157-187), (C-Term) antibodyKLK7 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB6441 unconjugated
anti-Kallikrein 7 (KLK7) (AA 67-97) antibodyKLK7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB6117 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Rat
ELISA, 0.1-0.5 μg/mL, Rat
1. Egelrud, T. Purification and preliminary characterization of stratum corneum chymotryptic enzyme: a proteinase that may be involved in desquamation. J. Invest. Derm. 101: 200-204, 1993. 2. Gan, L., Lee, I., Smith, R., Argonza-Barrett, R., Lei, H., McCuaig, J., Moss, P., Paeper, B., Wang, K. Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region. Gene 257: 119-130, 2000. 3. Hansson, L., Stromqvist, M., Backman, A., Wallbrandt, P., Carlstein, A., Egelrud, T. Cloning, expression, and characterization of stratum corneum chymotryptic enzyme: a skin-specific human serine proteinase. J. Biol. Chem. 269: 19420-19426, 1994. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Kallikrein 7 (KLK7)
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别名
- Klk7
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背景
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Synonyms: Platelet basic protein, PBP, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7, PPBP, CTAP3, CXCL7, SCYB7, TGB1, THBGB1, NAP-2
Background: Kallikrein-related peptidase 7 (KLK7) is a serine protease that in humans is encoded by the KLK7 gene. KLK7 is a chymotrypsin-like serine protease of the member of peptidase S1 family. It is synthesized with a signal peptide of 22 amino acids (aa 1-22) and a propeptide region (aa 23-29) that are subsequently cleaved to generate the mature form. Human KLK7 displays about 40 to 60 % amino acid homology with other members of the family. It cleaves proteins with aromatic side chains in the P1 position. KLK7 is abundantly expressed in the skin and is also present in the brain, mammary gland, cerebellum, spinal cord, and kidney. Lower levels of expression have been reported in in salivary glands, uterus, thymus, thyroid, placenta, trachea, and testis. Its levels are shown to be up-regulated in ovarian carcinoma, especially late-stage serous carcinoma. Less differentiated tumors of more advanced stage show higher level KLK7 expression. KLK7 activity is inhibited by zinc and copper ions
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分子量
- 38 kDa
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基因ID
- 292852
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UniProt
- P36373
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途径
- Complement System
抗原
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