HGS 抗体 (AA 3-777)
Quick Overview for HGS 抗体 (AA 3-777) (ABIN7601207)
抗原
See all HGS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 3-777
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原理
- Anti-HGS Antibody Picoband® (monoclonal, 6C2E1)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-HGS Antibody Picoband® (monoclonal, 6C2E1) (ABIN7601207). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HGS recombinant protein (Position: R3-D777).
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亚型
- IgG1
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anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (AA 513-612) antibody
HGS 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 6D11 unconjugated
anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (C-Term) antibodyHGS 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (Internal Region) antibodyHGS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (Internal Region) antibodyHGS 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) antibodyHGS 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (AA 513-612) antibodyHGS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (AA 451-500) antibodyHGS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (AA 301-350) antibodyHGS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (AA 548-777) antibodyHGS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) antibodyHGS 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 3H7 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Asao, H., Sasaki, Y., Arita, T., Tanaka, N., Endo, K., Kasai, H., Takeshita, T, Endo, Y., Fujita, T., Sugamura, K. Hrs is associated with STAM, a signal-transducing adaptor molecule: its suppressive effect on cytokine-induced cell growth. J. Biol. Chem. 272: 32785-32791, 1997. 2. Gutmann, D. H., Haipek, C. A., Burke, S. P., Sun, C.-X., Scoles, D. R., Pulst, S. M. The NF2 interactor, hepatocyte growth factor-regulated tyrosine kinase substrate (HRS), associates with merlin in the 'open' conformation and suppresses cell growth and motility. Hum. Molec. Genet. 10: 825-834, 2001. 3. Komada, M., Masaki, R., Yamamoto, A., Kitamura, N. Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomes. J. Biol. Chem. 272: 20538-20544, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))
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别名
- HGS
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背景
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Synonyms: Bcl-2 homologous antagonist/killer, Apoptosis regulator BAK, Bcl-2-like protein 7, Bcl2-L-7, BAK1, BAK, BCL2L7, CDN1
Tissue Specificity: Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
Background: Hepatocyte growth factor-regulated tyrosine kinase substrate is an enzyme that in humans is encoded by the HGS gene. It is mapped to 17q25.3. The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.
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分子量
- 110 kDa
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基因ID
- 9146
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UniProt
- O14964
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途径
- EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Synaptic Vesicle Exocytosis, EGFR Downregulation
抗原
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