RAD21 抗体 (AA 292-529)
Quick Overview for RAD21 抗体 (AA 292-529) (ABIN7601152)
抗原
See all RAD21 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 292-529
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原理
- Anti-RAD21 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-RAD21 Antibody Picoband® (ABIN7601152). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RAD21 recombinant protein (Position: D292-K529).
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亚型
- IgG
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anti-RAD21 Homolog (RAD21) (Center) antibody
RAD21 适用: 人, 小鼠 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAD21 Homolog (RAD21) antibodyRAD21 适用: 人 WB, IHC, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-RAD21 Homolog (RAD21) (AA 287-403) antibodyRAD21 适用: 人, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1B6D1 unconjugated
anti-RAD21 Homolog (RAD21) (N-Term) antibodyRAD21 适用: 人, 小鼠 WB, IF 宿主: 小鼠 Monoclonal unconjugated Recombinant Antibody
anti-RAD21 Homolog (RAD21) (C-Term) antibodyRAD21 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAD21 Homolog (RAD21) (AA 373-422) antibodyRAD21 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 猴, 豚鼠, 小鸡, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD21 Homolog (RAD21) antibodyRAD21 适用: 人 WB, ChIP 宿主: 兔 Monoclonal unconjugated
anti-RAD21 Homolog (RAD21) (C-Term) antibodyRAD21 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-RAD21 Homolog (RAD21) (C-Term) antibodyRAD21 适用: 人, 小鼠, Hamster WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RAD21 Homolog (RAD21) (AA 531-631) antibodyRAD21 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bonora, E., Bianco, F., Cordeddu, L., Bamshad, M., Francescatto, L., Dowless, D., Stanghellini, V. Cogliandro, R. F., Lindberg, G., Mungan, Z., Cefle, K., Ozcelik, T., and 14 others. Mutations in RAD21 disrupt regulation of APOB in patients with chronic intestinal pseudo-obstruction. Gastroenterology 148: 771-782, 2015. 2. Boyle, M. I., Jespersgaard, C., Nazaryan, L., Bisgaard, A.-M., Tumer, Z. A novel RAD21 variant associated with intrafamilial phenotypic variation in Cornelia de Lange syndrome--review of the literature. (Letter) Clin. Genet. 91: 647-649, 2017. 3. Deardorff, M. A., Wilde, J. J., Albrecht, M., Dickinson, E., Tennstedt, S., Braunholz, D., Monnich, M., Yan, Y., Xu, W., Gil-Rodriguez, M. C., Clark, D., Hakonarson, H., and 15 others. RAD21 mutations cause a human cohesinopathy. Am. J. Hum. Genet. 90: 1014-1027, 2012. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RAD21 (RAD21 Homolog (RAD21))
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别名
- RAD21
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背景
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Synonyms: Tubulin beta chain, Tubulin beta-5 chain, TUBB, TUBB5, OK/SW-cl.56
Tissue Specificity: Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Background: Double-strand-break repair protein rad21 homolog is a protein that in humans is encoded by the RAD21 gene. The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
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分子量
- 72 kDa
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基因ID
- 5885
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UniProt
- O60216
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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