PDGFC 抗体 (AA 288-345)
Quick Overview for PDGFC 抗体 (AA 288-345) (ABIN7601106)
抗原
See all PDGFC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 288-345
-
原理
- Anti-PDGFC Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-PDGFC Antibody Picoband® (ABIN7601106). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human PDGFC recombinant protein (Position: L288-G345).
-
亚型
- IgG
-
-
anti-Platelet-Derived Growth Factor C (PDGFC) (AA 61-110) antibody
PDGFC 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Derived Growth Factor C (PDGFC) (AA 201-300) antibodyPDGFC 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Derived Growth Factor C (PDGFC) (AA 235-345) antibodyPDGFC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Derived Growth Factor C (PDGFC) antibodyPDGFC 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Derived Growth Factor C (PDGFC) (AA 236-345) antibodyPDGFC 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Platelet-Derived Growth Factor C (PDGFC) (AA 1-345) antibodyPDGFC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Platelet-Derived Growth Factor C (PDGFC) (AA 23-345) antibodyPDGFC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Derived Growth Factor C (PDGFC) (AA 74-103) antibodyPDGFC 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Derived Growth Factor C (PDGFC) (AA 166-345) antibodyPDGFC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Derived Growth Factor C (PDGFC) (AA 235-345) antibodyPDGFC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ding, H., Wu, X., Bostrom, H., Kim, I., Wong, N., Tsoi, B., O'Rourke, M., Koh, G. Y., Soriano, P., Betsholtz, C., Hart, T. C., Marazita, M. L., Field, L. L., Tam, P. P. L., Nagy, A. A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling. Nature Genet. 36: 1111-1116, 2004. 2. Fredriksson, L., Li, H., Fieber, C., Li, X., Eriksson, U. Tissue plasminogen activator is a potent activator of PDGF-CC. EMBO J. 23: 3793-3802, 2004. 3. Gilbertson, D. G., Duff, M. E., West, J. W., Kelly, J. D., Sheppard, P. O., Hofstrand, P. D., Gao, Z., Shoemaker, K., Bukowski, T. R., Moore, M., Feldhaus, A. L., Humes, J. M., Palmer, T. E., Hart, C. E. Platelet-derived growth factor C (PDGF-C), a novel growth factor that binds PDGF alpha and beta receptor. J. Biol. Chem. 276: 27406-27414, 2001. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- PDGFC (Platelet-Derived Growth Factor C (PDGFC))
-
别名
- PDGFC
-
背景
-
Synonyms: NADPH oxidase 5, NOX5
Tissue Specificity: Mainly expressed in pachytene spermatocytes of testis and in lymphocyte-rich areas of spleen and lymph nodes. Isoform v1 is expressed in spleen. Isoform v2 is expressed in testis. Also detected in ovary, placenta, pancreas, cardiac fibroblasts. Expressed in B-cells and prostate malignant cells. Isoform v1 and isoform v3 are expressed in epithelial colorectal adenocarcinoma cells. Isoform v2 and isoform v4 are expressed in endothelial cells. Isoform v1, isoform v2, isoform v3 and isoform v4 are expressed in pulmonary artery smooth muscle cells. Isoform v2 and isoform v5 are expressed in microvascular endothelial cells (at protein level).
Background: Platelet-derived growth factor C, also known as PDGF-C, is a 345-amino acid protein that in humans is encoded by the PDGFC gene. The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene.
-
分子量
- 39 kDa
-
基因ID
- 56034
-
途径
- RTK signaling, Platelet-derived growth Factor Receptor Signaling
抗原
-
