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MUS81 抗体 (AA 283-483)

This 兔 多克隆 anti-MUS81 antibody specifically detects MUS81 in ELISA 和 WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7601094
发货至: 中国
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Quick Overview for MUS81 抗体 (AA 283-483) (ABIN7601094)

抗原

See all MUS81 抗体
MUS81 (MUS81 Endonuclease Homolog (MUS81))

适用

  • 18
  • 6
  • 5
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 17
  • 1

克隆类型

  • 18
多克隆

标记

  • 14
  • 2
  • 1
  • 1
This MUS81 antibody is un-conjugated

应用范围

  • 11
  • 7
  • 5
  • 4
  • 1
  • 1
ELISA, Western Blotting (WB)
  • 抗原表位

    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 283-483

    原理

    Anti-MUS81 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-MUS81 Antibody (ABIN7601094). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MUS81 recombinant protein (Position: H283-R483).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    MUS81 (MUS81 Endonuclease Homolog (MUS81))

    别名

    MUS81

    背景

    Synonyms: Lipopolysaccharide-binding protein, LBP, Lbp,

    Tissue Specificity: Detected in blood serum (at protein level).

    Background: Crossover junction endonuclease MUS81 is an enzyme that in humans is encoded by the MUS81 gene. This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.

    分子量

    52-72 kDa

    基因ID

    80198

    途径

    DNA Damage Repair
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