Poliovirus Receptor 抗体 (AA 28-331)
Quick Overview for Poliovirus Receptor 抗体 (AA 28-331) (ABIN7601070)
抗原
See all Poliovirus Receptor (PVR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 28-331
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原理
- Anti-Poliovirus Receptor/PVR Antibody Picoband® (monoclonal, 3B11E9)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Poliovirus Receptor/PVR Antibody Picoband® (monoclonal, 3B11E9) (ABIN7601070). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Poliovirus Receptor/PVR recombinant protein (Position: D28-E331).
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亚型
- IgG2b
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anti-Poliovirus Receptor (PVR) (AA 21-343) antibody
PVR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6D2D6 unconjugated
anti-Poliovirus Receptor (PVR) (AA 22-255) antibodyPVR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) antibodyPVR 适用: 小鼠 ELISA, FACS 宿主: 兔 Chimeric 3F1 unconjugated Recombinant Antibody
anti-Poliovirus Receptor (PVR) (AA 1-417) antibodyPVR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 56-309) antibodyPVR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 220-345) antibodyPVR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (Internal Region) antibodyPVR 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 21-343) antibodyPVR 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM146 unconjugated
anti-Poliovirus Receptor (PVR) (AA 314-342) antibodyPVR 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) antibodyPVR 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Bottino, C., Castriconi, R., Pende, D., Rivera, P., Nanni, M., Carnemolla, B., Cantoni, C., Grassi, J., Marcenaro, S., Reymond, N., Vitale, M., Moretta, L., Lopez, M., Moretta, A. Identification of PVR (CD155) and nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule. J. Exp. Med. 198: 557-567, 2003. 2. Fuchs, A., Cella, M., Giurisato, E., Shaw, A. S., Colonna, M. Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). J. Immun. 172: 3994-3998, 2004. 3. Gromeier, M., Solecki, D., Patel, D. D., Wimmer, E. Expression of the human poliovirus receptor/CD155 gene during development of the central nervous system: implications for the pathogenesis of poliomyelitis. Virology 273: 248-257, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Poliovirus Receptor (PVR)
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别名
- PVR
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背景
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Synonyms: Major vault protein, MVP, Lung resistance-related protein, MVP, LRP
Tissue Specificity: Present in most normal tissues. Higher expression observed in epithelial cells with secretory and excretory functions, as well as in cells chronically exposed to xenobiotics, such as bronchial cells and cells lining the intestine. Overexpressed in many multidrug-resistant cancer cells.
Background: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 70-80 kDa
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基因ID
- 5817
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UniProt
- P15151
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
抗原
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