EPH Receptor B2 抗体 (AA 278-540)
Quick Overview for EPH Receptor B2 抗体 (AA 278-540) (ABIN7601057)
抗原
See all EPH Receptor B2 (EPHB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 278-540
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原理
- Anti-Eph receptor B2/EPHB2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Eph receptor B2/EPHB2 Antibody Picoband® (ABIN7601057). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Eph receptor B2/EPHB2 recombinant protein (Position: K278-K540).
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亚型
- IgG
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anti-EPH Receptor B2 (EPHB2) antibody
EPHB2 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 48CT12-6-4 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 551-650) antibodyEPHB2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IHC (fro), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 226-325) antibodyEPHB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 17-200) antibodyEPHB2 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 2D12C6 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 1021-1050), (C-Term) antibodyEPHB2 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB01652 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 261-465) antibodyEPHB2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (C-Term) antibodyEPHB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) antibodyEPHB2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB15188 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 103-133), (N-Term) antibodyEPHB2 适用: 人, 小鼠 IHC (p) 宿主: 兔 Polyclonal RB01650 unconjugated
anti-EPH Receptor B2 (EPHB2) antibodyEPHB2 适用: 人 WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal 48CT12-6-4 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Attwood, B. K., Bourgognon, J.-M., Patel, S., Mucha, M., Schiavon, E., Skrzypiec, A. E., Young, K. W., Shiosaka, S., Korostynski, M., Piechota, M., Przewlocki, R., Pawlak, R. Neuropsin cleaves EphB2 in the amygdala to control anxiety. Nature 473: 372-375, 2011. 2. Berrou, E., Soukaseum, C., Favier, R., Adam, F., Elaib, Z., Kauskot, A., Bordet, J.-C., Ballerini, P., Loyau, S., Feng, M., Dias, K., Muheidli, A., and 9 others. A mutation of the human EPHB2 gene leads to a major platelet functional defect. Blood 132: 2067-2077, 2018. 3. Cisse, M., Halabisky, B., Harris, J., Devidze, N., Dubal, D. B., Sun, B., Orr, A., Lotz, G., Kim, D. H., Hamto, P., Ho, K., Yu, G.-Q., Mucke, L. Reversing EphB2 depletion rescues cognitive functions in Alzheimer model. Nature 469: 47-52, 2011. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- EPH Receptor B2 (EPHB2)
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别名
- EPHB2
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背景
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Synonyms: Ephrin type-B receptor 2 , Developmentally-regulated Eph-related tyrosine kinase, ELK-related tyrosine kinase, EPH tyrosine kinase 3, EPH-like kinase 5, EK5, Hek5, Renal carcinoma antigen NY-REN-47, Tyrosine-protein kinase TYRO5, Tyrosine-protein kinase receptor EPH-3, EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5
Tissue Specificity: Brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. Preferentially expressed in fetal brain.
Background: Ephrin type-B receptor 2 is a protein that in humans is encoded by the EPHB2 gene. This gene is mapped to 1p36.12. This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in biional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.
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分子量
- 117 kDa
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基因ID
- 2048
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UniProt
- P29323
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途径
- RTK signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
抗原
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