Caspase 10 抗体 (AA 271-482)
Quick Overview for Caspase 10 抗体 (AA 271-482) (ABIN7601039)
抗原
See all Caspase 10 (CASP10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 271-482
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原理
- Anti-Caspase-10/CASP10 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Caspase-10/CASP10 Antibody Picoband® (ABIN7601039). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Caspase-10/CASP10 recombinant protein (Position: K271-E482).
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亚型
- IgG
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anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 223-459) antibody
CASP10 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) antibodyCASP10 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 1-110) antibodyCASP10 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 1-110) antibodyCASP10 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 19-187) antibodyCASP10 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C9 unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) antibodyCASP10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 220-521) antibodyCASP10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 220-236), (N-Term) antibodyCASP10 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (C-Term) antibodyCASP10 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 430-479) antibodyCASP10 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Lee, H.-J., Pyo, J.-O., Oh, Y., Kim, H.-J., Hong, S., Jeon, Y.-J., Kim, H., Cho, D.-H., Woo, H.-N., Song, S., Nam, J.-H., Kim, H. J., Kim, K.-S., Jung, Y.-K.AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10.Nature Cell Biol. 9: 1303-1310, 2007. 2. Park, W. S., Lee, J. H., Shin, M. S., Park, J. Y., Kim, H. S., Lee, J. H., Kim, Y. S., Lee, S. N., Xiao, W., Park, C. H., Lee, S. H., Yoo, N. J., Lee, J. Y.Inactivating mutations of the caspase-10 gene in gastric cancer.Oncogene 21: 2919-2925, 2002. 3. Wang, J., Zheng, L., Lobito, A., Chan, F. K., Dale, J., Sneller, M., Yao, X., Puck, J. M., Straus, S. E., Lenardo, M. J.Inherited human caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II.Cell 98: 47-58, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
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别名
- CASP10
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背景
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Synonyms: Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha, CD235a, GYPA, GPA
Tissue Specificity: Renal medulla and colon. Predominantly in the inner medulla. Expressed in basal layer of epidermal keratinocytes.
Background: Caspase-10 is an enzyme that, in humans, is encoded by the CASP10 gene. The Caspase 10 gene contains 11 exons and spans about 48 kb. This gene is mapped to 2q33.1. It is transcribed in the centromere-to-telomere ion.This gene encodes a protein that is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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分子量
- 59 kDa
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基因ID
- 843
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UniProt
- Q92851
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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