UBAP2L 抗体 (AA 271-439)
Quick Overview for UBAP2L 抗体 (AA 271-439) (ABIN7601038)
抗原
See all UBAP2L 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 271-439
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原理
- Anti-UBAP2L Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-UBAP2L Antibody Picoband® (ABIN7601038). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human UBAP2L recombinant protein (Position: A271-S439).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bordeleau, M.-E., Aucagne, R., Chagraoui, J., Girard, S., Mayotte, N., Bonneil, E., Thibault, P., Pabst, C., Bergeron, A., Barabe, F., Hebert, J., Sauvageau, M., Boutonnet, C., Meloche, S., Sauvageau, G. UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity. Blood 124: 2362-2369, 2014. 2. Gross, M. B. Personal Communication. Baltimore, Md. 7/17/2015. 3. Marenholz, I., Zirra, M., Fischer, D. F., Backendorf, C., Ziegler, A., Mischke, D. Identification of human epidermal differentiation complex (EDC)-encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library. Genome Res. 11: 341-355, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- UBAP2L (Ubiquitin Associated Protein 2-Like (UBAP2L))
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别名
- UBAP2L
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背景
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Synonyms: Gastrotropin, GT, Fatty acid-binding protein 6, Ileal lipid-binding protein, ILBP, Intestinal 15 kDa protein, I-15P, Intestinal bile acid-binding protein, I-BABP, FABP6, ILBP, ILLBP
Tissue Specificity: Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa.
Background: Ubiquitin-associated protein 2-like is a protein that in humans is encoded by the UBAP2L gene. Ubiquitin-associated protein 2-like (UBAP2L), which contains a ubiquitin-associated (UBA) domain near its N-terminus, has been indicated in the pathogenesis of several human cancers, including multiple myeloma, hepatocellular carcinoma, and malignant ovarian tumors. UBAP2L is closely associated with tumor growth and metastasis. UBAP2L has a key role in glioma cell growth and may act as an oncogene to promote malignant glioma development. UBAP2L also plays an important role in breast cancer cell proliferation and might serve as a potential target for breast cancer treatment. UBAP2L plays a critical role in the maintenance of the metastatic ability of hepatocellular carcinoma (HCC) cells via SNAIL1 Regulation and is predictive of a poor clinical outcome.
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分子量
- 150 kDa
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基因ID
- 9898
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UniProt
- Q14157
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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