CoREST 抗体 (AA 270-485)
Quick Overview for CoREST 抗体 (AA 270-485) (ABIN7601035)
抗原
See all CoREST (RCOR1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 270-485
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原理
- Anti-CoREST/RCOR1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CoREST/RCOR1 Antibody Picoband® (ABIN7601035). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CoREST/RCOR1 recombinant protein (Position: N270-S485).
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亚型
- IgG
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anti-REST Corepressor 1 (RCOR1) antibody
RCOR1 适用: 人 WB, IHC, IP, ChIP 宿主: 兔 Monoclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (AA 256-485) antibodyRCOR1 适用: 人 WB, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (N-Term) antibodyRCOR1 适用: 人, 小鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (AA 394-482) antibodyRCOR1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (N-Term) antibodyRCOR1 适用: 人, 小鼠, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (AA 109-293) antibodyRCOR1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (C-Term) antibodyRCOR1 适用: 人, 小鼠, 犬, 豚鼠, Cow, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) antibodyRCOR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (C-Term) antibodyRCOR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (AA 101-130), (N-Term) antibodyRCOR1 适用: 人 WB 宿主: 兔 Polyclonal RB36780 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Andres, M. E., Burger, C., Peral-Rubio, M. J., Battaglioli, E., Anderson, M. E., Grimes, J., Dallman, J., Ballas, N., Mandel, G. CoREST: a functional corepressor required for regulation of neural-specific gene expression. Proc. Nat. Acad. Sci. 96: 9873-9878, 1999. 2. Gocke, C. B., Yu, H. ZNF198 stabilizes the LSD1-CoREST-HDAC1 complex on chromatin through its MYM-type zinc fingers. PLoS One 3: E3255, 2008. Note: Electronic Article. 3. Lee, M. G., Wynder, C., Cooch, N., Shiekhattar, R. An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation. Nature 437: 432-435, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CoREST (RCOR1) (REST Corepressor 1 (RCOR1))
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别名
- RCOR1
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背景
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Synonyms: Proliferation-associated protein 2G4,Cell cycle protein p38-2G4 homolog,hG4-1,ErbB3-binding protein 1,PA2G4,EBP1,
Tissue Specificity: Isoform 2 is undetectable whereas isoform 1 is strongly expressed in cancer cells (at protein level). Isoform 1 and isoform 2 are widely expressed, including heart, brain, lung, pancreas, skeletal muscle, kidney, placenta and liver. .
Background: REST corepressor 1 also known as CoREST is a protein that in humans is encoded by the RCOR1 gene. This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor).
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分子量
- 65 kDa
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基因ID
- 23186
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途径
- Regulation of Hormone Metabolic Process, Chromatin Binding
抗原
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