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UGT1A6 抗体 (AA 27-251)

This anti-UGT1A6 antibody is a 兔 多克隆 antibody detecting UGT1A6 in ELISA, WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN7601003
发货至: 中国

Quick Overview for UGT1A6 抗体 (AA 27-251) (ABIN7601003)

抗原

See all UGT1A6 抗体
UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

适用

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宿主

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克隆类型

  • 23
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多克隆

标记

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This UGT1A6 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 5
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    AA 27-251

    原理

    Anti-UGT1A6 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-UGT1A6 Antibody (ABIN7601003). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human UGT1A6 recombinant protein (Position: D27-S251).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

    别名

    UGT1A6

    背景

    Synonyms: "UDP-glucuronosyltransferase 1-5, UDPGT 1-5, UGT1*5, UGT1-05, UGT1.5, UDP-glucuronosyltransferase 1-E, UGT-1E, UGT1E, UDP-glucuronosyltransferase 1A5, UGT1A5, GNT1, UGT1

    Tissue Specificity: Expressed in skin. Isoforms 1 and 3 are expressed in kidney and liver. Isoform 1 but not isoform 2 is expressed in colon, esophagus and small intestine.

    Background: UDP-glucuronosyltransferase 1-6 is an enzyme that in humans is encoded by the UGT1A6 gene. It is mapped to 2q37.1. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.

    分子量

    55-61 kDa

    基因ID

    54578

    UniProt

    P19224

    途径

    Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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