UGT1A6 抗体 (AA 27-251)
Quick Overview for UGT1A6 抗体 (AA 27-251) (ABIN7601003)
抗原
See all UGT1A6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-251
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原理
- Anti-UGT1A6 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-UGT1A6 Antibody Picoband® (ABIN7601003). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human UGT1A6 recombinant protein (Position: D27-S251).
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亚型
- IgG
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anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) (Center) antibody
UGT1A6 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) (AA 65-270) antibodyUGT1A6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) (AA 278-410) antibodyUGT1A6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) (AA 44-143) antibodyUGT1A6 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) (AA 1-532) antibodyUGT1A6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) (AA 44-143) antibodyUGT1A6 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4A10 unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) (C-Term) antibodyUGT1A6 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) (AA 8-197) antibodyUGT1A6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) (C-Term) antibodyUGT1A6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) (C-Term) antibodyUGT1A6 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 斑马鱼, Cow, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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"Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
"1. Mackenzie PI, Owens IS, Burchell B, Bock KW, Bairoch A, Bélanger A, Fournel-Gigleux S, Green M, Hum DW, Iyanagi T, Lancet D, Louisot P, Magdalou J, Chowdhury JR, Ritter JK, Schachter H, Tephly TR, Tipton KF, Nebert DW (August 1997). "The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence". Pharmacogenetics. 7 (4): 255-69. 2. Ritter JK, Chen F, Sheen YY, Tran HM, Kimura S, Yeatman MT, Owens IS (February 1992). "A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini". The Journal of Biological Chemistry. 267 (5): 3257-61. 3. Shrestha B, Reed JM, Starks PT, Kaufman GE, Goldstone JV, Roelke ME, O'Brien SJ, Koepfli KP, Frank LG, Court MH (2011). Zanger U (ed.). "Evolution of a major drug metabolizing enzyme defect in the domestic cat and other felidae: phylogenetic timing and the role of hypercarnivory". PLoS One. 6 (3): e18046. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))
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别名
- UGT1A6
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背景
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Synonyms: "UDP-glucuronosyltransferase 1-5, UDPGT 1-5, UGT1*5, UGT1-05, UGT1.5, UDP-glucuronosyltransferase 1-E, UGT-1E, UGT1E, UDP-glucuronosyltransferase 1A5, UGT1A5, GNT1, UGT1
Tissue Specificity: Expressed in skin. Isoforms 1 and 3 are expressed in kidney and liver. Isoform 1 but not isoform 2 is expressed in colon, esophagus and small intestine.
Background: UDP-glucuronosyltransferase 1-6 is an enzyme that in humans is encoded by the UGT1A6 gene. It is mapped to 2q37.1. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.
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分子量
- 55-61 kDa
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基因ID
- 54578
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UniProt
- P19224
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途径
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
抗原
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