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UGT1A6 抗体 (C-Term)

UGT1A6 适用: 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 斑马鱼, 马, 绵羊, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776828
发货至: 中国
  • 抗原 See all UGT1A6 抗体
    UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))
    抗原表位
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 23
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 斑马鱼, 马, 绵羊, Cow
    宿主
    • 20
    • 3
    克隆类型
    • 21
    • 2
    多克隆
    标记
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UGT1A6 antibody is un-conjugated
    应用范围
    • 10
    • 8
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    APHLRPAAHD LTWYQYHSLD VIGFLLAVVL TVAFITFKCC AYGYRKCLGK
    预测反应
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 92%
    产品特性
    This is a rabbit polyclonal antibody against UGT1A6. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human UGT1A6
    Top Product
    Discover our top product UGT1A6 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 532 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))
    别名
    UGT1A6 (UGT1A6 产品)
    别名
    GNT1 antibody, HLUGP antibody, HLUGP1 antibody, UDPGT antibody, UDPGT 1-6 antibody, UGT1 antibody, UGT1A6S antibody, UGT1F antibody, UGT1A10 antibody, UGT1A6 antibody, UGT1A7 antibody, UGT1A8 antibody, UGT1A9 antibody, DKFZP469F071 antibody, UGT1A5 antibody, UGT antibody, Udpgt antibody, Ugt1 antibody, Ugt1a7 antibody, UGT1-06 antibody, UGT1.6 antibody, Ugt1a6b antibody, Ugt1a6 antibody, UDP glucuronosyltransferase family 1 member A6 antibody, UDP glucuronosyltransferase family 1 member A1 antibody, UDP glucuronosyltransferase 1 family, polypeptide A6 antibody, UDP-glucuronosyltransferase 1-1 antibody, UDP glucuronosyltransferase 1 family, polypeptide A6 S homeolog antibody, UDP-glucuronosyltransferase 1-6 antibody, UGT1A6 antibody, UGT1A1 antibody, LOC739942 antibody, ugt1a6.S antibody, ugt1a6 antibody, LOC100481084 antibody, Ugt1a6 antibody, UGT1-6 antibody, LOC100731122 antibody
    背景
    UGT1A6 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.
    Alias Symbols: GNT1, HLUGP, HLUGP1, MGC29860, UDPGT, UGT1, UGT1F, UGT1A6S, UDPGT 1-6
    Protein Size: 532
    分子量
    58 kDa
    基因ID
    54578
    NCBI登录号
    NM_001072, NP_001063
    UniProt
    P19224
    途径
    Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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