Phospholipase C beta 2 抗体 (AA 27-1185)
Quick Overview for Phospholipase C beta 2 抗体 (AA 27-1185) (ABIN7600992)
抗原
See all Phospholipase C beta 2 (PLCb2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-1185
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原理
- Anti-PLCB2 Antibody Picoband®
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产品特性
- Anti-PLCB2 Antibody Picoband® (ABIN7600992). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PLCB2 recombinant protein (Position: D27-L1185). Human PLCB2 shares 85.7% and 85.3% amino acid (aa) sequence identity with mouse and rat PLCB2, respectively.
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anti-phospholipase C beta 2 (PLCb2) (AA 1-250) antibody
PLCb2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C beta 2 (PLCb2) (AA 1-250) antibodyPLCb2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C beta 2 (PLCb2) (AA 1-250) antibodyPLCb2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C beta 2 (PLCb2) (AA 1031-1185) antibodyPLCb2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C beta 2 (PLCb2) (AA 1-199) antibodyPLCb2 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-phospholipase C beta 2 (PLCb2) (Internal Region) antibodyPLCb2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C beta 2 (PLCb2) (AA 1-199) antibodyPLCb2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C beta 2 (PLCb2) (AA 174-202), (N-Term) antibodyPLCb2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17392 unconjugated
anti-phospholipase C beta 2 (PLCb2) (AA 401-500) antibody (AbBy Fluor® 647)PLCb2 适用: 人, 小鼠 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 647
anti-phospholipase C beta 2 (PLCb2) antibodyPLCb2 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Lee, S. B., Rao, A. K., Lee, K.-H., Yang, X., Bae, Y. S., Rhee, S. G. Decreased expression of phospholipase C-b2 isozyme in human platelets with impaired function. Blood 88: 1684-1691, 1996. 2. Li, Z., Jiang, H., Xie, W., Zhang, Z., Smrcka, A. V., Wu, D. Roles of PLC-beta-2 and -beta-3 and PI3K-gamma in chemoattractant-mediated signal transduction. Science 287: 1046-1049, 2000. 3. Mao, G. F., Vaidyula, V. R., Kunapuli, S. P., Rao, A. K. Lineage-specific defect in gene expression in human platelet phospholipase C-beta-2 deficiency. Blood 99: 905-911, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Phospholipase C beta 2 (PLCb2) (phospholipase C beta 2 (PLCb2))
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别名
- PLCB2
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背景
- 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 is an enzyme that in humans is encoded by the PLCB2 gene. The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.
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分子量
- 140 kDa
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基因ID
- 5330
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UniProt
- Q00722
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途径
- WNT signaling, Thyroid Hormone Synthesis, CXCR4-mediated Signaling Events, G-protein mediated Events, Thromboxane A2 Receptor Signaling
抗原
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