LGR5 抗体 (AA 26-907)
Quick Overview for LGR5 抗体 (AA 26-907) (ABIN7600974)
抗原
See all LGR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-907
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原理
- Anti-LGR5 Antibody Picoband®
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产品特性
- Anti-LGR5 Antibody Picoband® (ABIN7600974). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LGR5 recombinant protein (Position: R26-L907). Human LGR5 shares 87% and 87.1% amino acid (aa) sequence identity with mouse and rat LGR5, respectively.
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anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 810-907) antibody
LGR5 适用: 人, 小鼠 WB, FACS, ELISA, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 443-473) antibodyLGR5 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB14555 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 22-178) antibodyLGR5 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2B5B9 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 250-550) antibodyLGR5 适用: 人, 小鼠 WB, FACS, IHC, IF, IP 宿主: 小鼠 Monoclonal 2A2 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 443-473) antibodyLGR5 适用: 人 WB, FACS, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 689-719) antibodyLGR5 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (Cytoplasmic Domain) antibodyLGR5 适用: 人 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 824-907) antibodyLGR5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 241-352) antibodyLGR5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) antibodyLGR5 适用: 人 WB, FACS, ELISA 宿主: 兔 Monoclonal 4H8 unconjugated Recombinant Antibody
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Barker, N., Ridgway, R. A., van Es, J. H., van de Wetering, M., Begthel, H., van den Born, M., Danenberg, E., Clarke, A. R., Sansom, O. J., Clevers, H. Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 457: 608-611, 2009. 2. Barker, N., van Es, J. H., Kuipers, J., Kujala, P., van den Born, M., Cozijnsen, M., Haegebarth, A., Korving, J., Begthel, H., Peters, P. J., Clevers, H. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449: 1003-1007, 2007. 3. de Lau, W., Barker, N., Low, T. Y., Koo, B.-K., Li, V. S. W., Teunissen, H., Kujala, P., Haegebarth, A., Peters, P. J., van de Wetering, M., Stange, D. E, van Es, J. E., Guardavaccaro, D., Schasfoort, R. B. M., Mohri, Y., Nishimori, K., Mohammed, S., Heck, A. J. R., Clevers, H. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature 476: 293-297, 2011. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
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别名
- LGR5
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背景
- Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) also known as G-protein coupled receptor 49 (GPR49) or G-protein coupled receptor 67 (GPR67) is a protein that in humans is encoded by the LGR5 gene. The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
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分子量
- 130 kDa
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基因ID
- 8549
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UniProt
- O75473
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途径
- WNT signaling
抗原
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