HLA-DRA 抗体 (AA 26-254)
Quick Overview for HLA-DRA 抗体 (AA 26-254) (ABIN7600950)
抗原
See all HLA-DRA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 26-254
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原理
- Anti-HLA-DR/HLA-DRA Antibody Picoband® (monoclonal, 8I10H1)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-HLA-DR/HLA-DRA Antibody Picoband® (monoclonal, 8I10H1) (ABIN7600950). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HLA-DR/HLA-DRA recombinant protein (Position: I26-L254).
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亚型
- IgG1
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anti-HLA Class II DR alpha (HLA-DRA) (AA 26-254) antibody
HLA-DRA 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 1C11A5 unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 26-216) antibodyHLA-DRA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 27-216) antibodyHLA-DRA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 1-254) antibodyHLA-DRA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal 19-26-1-same as MB-26-1 unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-470R unconjugated Recombinant Antibody
anti-HLA Class II DR alpha (HLA-DRA) (AA 26-221) antibody (APC)HLA-DRA 适用: 兔 WB, IHC 宿主: 豚鼠 Polyclonal APC
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人, Cow, Cat FACS, IF 宿主: 小鼠 Monoclonal 169-1B5-2 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Tjernlund U, Scheynius A, Johansson C, et al. (1989). "T-cell response to purified protein derivative after removal of Langerhans' cells from epidermal cell suspensions containing keratinocytes expressing class II transplantation antigens". Scand. J. Immunol. 28 (6): 667-73. 2. Chelladurai, M., Honn, K. V., Walz, D. A. HLA-DR is a procoagulant. Biochem. Biophys. Res. Commun. 178: 467-473, 1991. 3. Das, H. K., Lawrance, S. K., Weissman, S. M. Structure and nucleotide sequence of the heavy chain gene of HLA-DR. Proc. Nat. Acad. Sci. 80: 3543-3547, 1983. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HLA-DRA (HLA Class II DR alpha (HLA-DRA))
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别名
- HLA-DRA
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背景
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Synonyms: Exportin-1, Exp1, Chromosome region maintenance 1 protein homolog, XPO1, CRM1
Tissue Specificity: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. Not expressed in the kidney.
Background: HLA class II histocompatibility antigen, DR alpha chainis aproteinthat in humans is encoded by the HLA-DRAgene. It is mapped to 6p21.32. HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
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分子量
- 35-37 kDa
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基因ID
- 3122
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UniProt
- P01903
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途径
- TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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