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ARHGEF7 抗体 (AA 25-637)

This anti-ARHGEF7 antibody is a 兔 多克隆 antibody detecting ARHGEF7 in WB, ELISA, IHC, IF, ICC 和 FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7600917
发货至: 中国

Quick Overview for ARHGEF7 抗体 (AA 25-637) (ABIN7600917)

抗原

See all ARHGEF7 抗体
ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

适用

人, 大鼠, 小鼠

宿主

  • 49
  • 3

克隆类型

  • 50
  • 2
多克隆

标记

  • 23
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ARHGEF7 antibody is un-conjugated

应用范围

  • 26
  • 23
  • 13
  • 13
  • 10
  • 8
  • 7
  • 5
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 25-637

    原理

    Anti-ARHGEF7 Antibody Picoband®

    产品特性

    Anti-ARHGEF7 Antibody Picoband® (ABIN7600917). Tested in WB, IHC, ICC/IF, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ARHGEF7 recombinant protein (Position: S25-N637). Human ARHGEF7 shares 90.4% amino acid (aa) sequence identity with mouse ARHGEF7.
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bagrodia, S., Taylor, S. J., Jordon, K. A., Van Aelst, L., Cerione, R. A. A novel regulator of p21-activated kinases. J. Biol. Chem. 273: 23633-23636, 1998. 2. Feng, Q., Baird, D., Peng, X., Wang, J., Ly, T., Guan, J.-L., Cerione, R. A. Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth. Nature Cell Biol. 8: 945-956, 2006. 3. Manser, E., Loo, T.-H., Koh, C.-G., Zhao, Z.-S., Chen, X.-Q., Tan, L., Tan, I., Leung, T., Lim, L. PAK kinases are ly coupled to the PIX family of nucleotide exchange factors. Molec. Cell 1: 183-192, 1998.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

    别名

    ARHGEF7

    背景

    Rho guanine nucleotide exchange factor 7 is a protein that in humans is encoded by the ARHGEF7 gene. This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.

    分子量

    80 kDa

    基因ID

    8874

    UniProt

    Q14155

    途径

    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
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