ARHGEF7 抗体
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北京 101111
Quick Overview for ARHGEF7 抗体 (ABIN1169227)
抗原
See all ARHGEF7 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- anti-beta-Pix (mouse), pAb
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特异性
- Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms. Cross-reacts with human and rat beta-Pix.
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交叉反应 （详细）
- Cross-reacts with human and rat beta-Pix.
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产品特性
- Polyclonal Antibody. Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms. Cross-reacts with human and rat beta-Pix. Source: Rabbit. Applications: ELISA, ICC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant beta-Pix SH3 domain.
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7) antibody
ARHGEF7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7) (AA 1-250) antibodyARHGEF7 适用: 人 ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7) (AA 1-188) antibodyARHGEF7 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7) (AA 654-688) antibodyARHGEF7 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB56222 unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7) antibody (HRP)ARHGEF7 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7) antibody (FITC)ARHGEF7 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7) antibody (Biotin)ARHGEF7 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7) (AA 1-260) antibodyARHGEF7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7) (AA 102-190) antibodyARHGEF7 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7) (AA 1-646) antibodyARHGEF7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4.
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储存液
- Without preservative
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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有效期
- 6 months
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: "Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).
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- ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
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别名
- beta-Pix
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背景
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Alternate Names/Synonyms: ARHGEF7, Rho Guanine Nucleotide Exchange Factor 7, PAK-interacting Exchange Factor beta, p85SPR, COOL-1
Product Description: beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.
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UniProt
- Q9ES28
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
抗原
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