NEIL3 抗体 (AA 244-585)
Quick Overview for NEIL3 抗体 (AA 244-585) (ABIN7600870)
抗原
See all NEIL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 244-585
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原理
- Anti-NEIL3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NEIL3 Antibody Picoband® (ABIN7600870). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NEIL3 recombinant protein (Position: K244-K585).
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亚型
- IgG
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anti-Nei Endonuclease VIII-Like 3 (NEIL3) (AA 2-187) antibody
NEIL3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) antibodyNEIL3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (AA 292-320) antibodyNEIL3 适用: 人 WB 宿主: 兔 Polyclonal RB40413 unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) antibodyNEIL3 适用: 人 DB 宿主: 小鼠 Monoclonal 2627C1b unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人, 小鼠, 大鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bandaru, V., Sunkara, S., Wallace, S. S., Bond, J. P. A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII. DNA Repair 1: 517-529, 2002. 2. Morland, I., Rolseth, V., Luna, L., Rognes, T., Bjoras, M., Seeberg, E. Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA. Nucleic Acids Res. 30: 4926-4936, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))
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别名
- NEIL3
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背景
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Synonyms: Atypical chemokine receptor 2, C-C chemokine receptor D6, Chemokine receptor CCR-10, Chemokine receptor CCR-9, Chemokine-binding protein 2, Chemokine-binding protein D6, ACKR2, CCBP2, CCR10, CMKBR9, D6
Tissue Specificity: Found in endothelial cells lining afferent lymphatics in dermis and lymph nodes. Also found in lymph nodes subcapsular and medullary sinuses, tonsillar lymphatic sinuses and lymphatics in mucosa and submucosa of small and large intestine and appendix. Also found in some malignant vascular tumors. Expressed at high levels in Kaposi sarcoma-related pathologies. Expressed on apoptotic neutrophils (at protein level). Expressed primarily in placenta and fetal liver, and found at very low levels in the lung and lymph node.
Background: Nei endonuclease VIII-like 3 (E. coli) is a protein in humans that is encoded by the NEIL3 gene. NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
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分子量
- 70 kDa
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基因ID
- 55247
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途径
- DNA Damage Repair
抗原
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