RNF8 抗体 (AA 243-485)
Quick Overview for RNF8 抗体 (AA 243-485) (ABIN7600866)
抗原
See all RNF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 243-485
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原理
- Anti-RNF8 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RNF8 Antibody Picoband® (ABIN7600866). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RNF8 recombinant protein (Position: Q243-F485).
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亚型
- IgG
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anti-Ring Finger Protein 8 (RNF8) (AA 1-485) antibody
RNF8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (N-Term) antibodyVerified RNF8 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (C-Term) antibodyRNF8 适用: 人, 小鼠, 大鼠, Cow, 非洲爪蟾 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (C-Term) antibodyRNF8 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (AA 1-260) antibodyRNF8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (AA 1-485) antibodyRNF8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (AA 351-400) antibodyRNF8 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (AA 335-364) antibodyRNF8 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) (AA 1-485) antibodyRNF8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 8 (RNF8) antibodyRNF8 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22159 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bekker-Jensen, S., Rendtlew Danielsen, J., Fugger, K., Gromova, I., Nerstedt, A., Lukas, C., Bartek, J., Lukas, J., Mailand, N. HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes. Nature Cell Biol. 12: 80-86, 2010. Note: Erratum Nature Cell Biol. 12: 412 only, 2010. 2. Ishikawa, K., Nagase, T., Suyama, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 5: 169-176, 1998. 3. Kolas, N. K., Chapman, J. R., Nakada, S., Ylanko, J., Chahwan, R., Sweeney, F. D., Panier, S., Mendez, M., Wildenhain, J., Thomson, T. M., Pelletier, L., Jackson, S. P., Durocher, D. Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science 318: 1637-1640, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RNF8 (Ring Finger Protein 8 (RNF8))
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别名
- RNF8
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背景
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Synonyms: High affinity nerve growth factor receptor
Tissue Specificity: Isoform TrkA-I is found in most non-neuronal tissues. Isoform TrkA-II is primarily expressed in neuronal cells. TrkA-III is specifically expressed by pluripotent neural stem and neural crest progenitors.
Background: E3 ubiquitin-protein ligase RNF8 is an enzyme that in humans is encoded by the RNF8 gene. The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.
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分子量
- 65 kDa
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基因ID
- 9025
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UniProt
- O76064
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途径
- Production of Molecular Mediator of Immune Response
抗原
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