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CD5 抗体 (AA 24-494)

This anti-CD5 antibody is a 小鼠 单克隆 antibody detecting CD5 in WB 和 IHC. Suitable for 大鼠.
产品编号 ABIN7600841
发货至: 中国

Quick Overview for CD5 抗体 (AA 24-494) (ABIN7600841)

抗原

See all CD5 抗体
CD5

适用

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大鼠

宿主

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  • 1
小鼠

克隆类型

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单克隆

标记

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This CD5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

11B4
  • 抗原表位

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    AA 24-494

    原理

    Anti-CD5 Antibody Picoband® (monoclonal, 11B4)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-CD5 Antibody Picoband® (monoclonal, 11B4) (ABIN7600841). Tested in IHC, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived rat CD5 recombinant protein (Position: Q24-L494).

    亚型

    IgG1
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Rat
    1. Lundell, A.-C., Johansen, S., Adlerberth, I., Wold, A. E., Hesselmar, B., Rudin, A. High proportion of CD5+ B cells in infants predicts development of allergic disease. J. Immun. 193: 510-518, 2014. 2. Zhang, C., Xin, H., Zhang, W., Yazaki, P. J., Zhang, Z., Le, K., Li, W., Lee, H., Kwak, L., Forman, S., Jove, R., Yu, H. CD5 binds to interleukin-6 and induces a feed-forward loop with the transcription factor STAT3 in B cells to promote cancer. Immunity 44: 913-923, 2016.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CD5

    别名

    Cd5

    背景

    Synonyms: T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, CD5, CD5, LEU1

    Tissue Specificity: Brain, liver, placenta, lymphocytes and erythrocytes.

    Background: CD5 is a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. In humans, the gene is located on the long arm of chromosome 11. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    67 kDa

    基因ID

    54236
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