STRADB 抗体 (AA 24-411)
Quick Overview for STRADB 抗体 (AA 24-411) (ABIN7600831)
抗原
See all STRADB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-411
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原理
- Anti-STRADB Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-STRADB Antibody Picoband® (ABIN7600831). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human STRADB recombinant protein (Position: E24-E411).
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亚型
- IgG
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anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 319-418) antibody
STRADB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E11 unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (C-Term) antibodyVerified STRADB 适用: 人 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 212-418) antibodySTRADB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 251-350) antibodySTRADB 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 1-95) antibodySTRADB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 200-250) antibodySTRADB 适用: 人, Cow, 犬, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (C-Term) antibodySTRADB 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (Intermediate Domain) antibodySTRADB 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hadano, S., Yanagisawa, Y., Skaug, J., Fichter, K., Nasir, J., Martindale, D., Koop, B. F., Scherer, S. W., Nicholson, D. W., Rouleau, G. A., Ikeda, J.-E., Hayden, M. R. Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2. Genomics 71: 200-213, 2001. 2. Sanna, M. G., da Silva Correia, J., Luo, Y., Chuang, B., Paulson, L. M., Nguyen, B., Deveraux, Q. L., Ulevitch, R. J. ILPIP, a novel anti-apoptotic protein that enhances XIAP-mediated activation of JNK1 and protection against apoptosis. J. Biol. Chem. 277: 30454-30462, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- STRADB (STE20-Related Kinase Adaptor beta (STRADB))
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别名
- STRADB
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背景
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Synonyms: Transcription factor MafA, Pancreatic beta-cell-specific transcriptional activator, RIPE3b1 factor, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA
Tissue Specificity: Preferentially expressed in regulatory T-cells (Tregs).
Background: STE20-related kinase adapter protein beta is an enzyme that in humans is encoded by the STRADB gene. This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 33 kDa
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基因ID
- 55437
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UniProt
- Q9C0K7
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途径
- AMPK Signaling
抗原
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