Poliovirus Receptor 抗体 (AA 24-345)
Quick Overview for Poliovirus Receptor 抗体 (AA 24-345) (ABIN7600826)
抗原
See all Poliovirus Receptor (PVR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-345
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原理
- Anti-Poliovirus Receptor/PVR Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Poliovirus Receptor/PVR Antibody Picoband® (ABIN7600826). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Poliovirus Receptor/PVR recombinant protein (Position: R24-R345).
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亚型
- IgG
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anti-Poliovirus Receptor (PVR) (AA 21-343) antibody
PVR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6D2D6 unconjugated
anti-Poliovirus Receptor (PVR) (AA 22-255) antibodyPVR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) antibodyPVR 适用: 小鼠 ELISA, FACS 宿主: 兔 Chimeric 3F1 unconjugated Recombinant Antibody
anti-Poliovirus Receptor (PVR) (AA 1-417) antibodyPVR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 56-309) antibodyPVR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 220-345) antibodyPVR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (Internal Region) antibodyPVR 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 21-343) antibodyPVR 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM146 unconjugated
anti-Poliovirus Receptor (PVR) (AA 314-342) antibodyPVR 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) antibodyPVR 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Bottino, C., Castriconi, R., Pende, D., Rivera, P., Nanni, M., Carnemolla, B., Cantoni, C., Grassi, J., Marcenaro, S., Reymond, N., Vitale, M., Moretta, L., Lopez, M., Moretta, A. Identification of PVR (CD155) and nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule. J. Exp. Med. 198: 557-567, 2003. 2. Fuchs, A., Cella, M., Giurisato, E., Shaw, A. S., Colonna, M. Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). J. Immun. 172: 3994-3998, 2004. 3. Gromeier, M., Solecki, D., Patel, D. D., Wimmer, E. Expression of the human poliovirus receptor/CD155 gene during development of the central nervous system: implications for the pathogenesis of poliomyelitis. Virology 273: 248-257, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Poliovirus Receptor (PVR)
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别名
- PVR
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背景
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Synonyms: NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD314, KLRK1, D12S2489E, NKG2D
Tissue Specificity: Expressed in natural killer (NK) cells, CD8 (+) alpha-beta and gamma-delta T-cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Expressed in interferon-producing killer dendritic cells (IKDCs).
Background: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 60-80 kDa
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基因ID
- 52118
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
抗原
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